Soft Tissue

Soft Tissue

Soft tissue grafts are used to reinforce or reconstruct areas where weakness exists. These grafts can be from human donors or from another species, such as porcine or bovine. Soft tissue grafts have been growing in use at a rapid pace and are used for numerous procedures such as reinforcement of the rotator cuff, patellar tendon, Achilles tendon, quadriceps tendon, and tendon sheaths of the hand, wrist, foot and ankle.

Soft tissue grafts are used to reinforce or reconstruct areas where weakness exists. These grafts can be from human donors or from another species, such as porcine or bovine. Soft tissue grafts have been growing in use at a rapid pace and are used for numerous procedures such as reinforcement of the rotator cuff, patellar tendon, Achilles tendon, quadriceps tendon, and tendon sheaths of the hand, wrist, foot and ankle.

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Arthrex Amnion™ Matrix

Arthrex Amnion™ Matrix

Arthrex Amnion matrix is rich in growth factors and contains regenerative qualities that maintain the natural healing properties of amnion. Used as an anatomical barrier or wrap in a variety of orthopedic applications. Arthrex Amnion provides essential biological and mechanical protection while helping to prevent adhesion.¹
^Reference
^{1. Kim SS, Sohn SK, Lee KY, Lee MJ, Roh MS, Kim CH. Use of human amniotic membrane wrap in reducing perineural adhesions in a rabbit model of ulnar nerve neurorrhaphy. J Hand Surg Eur Vol. 2010;35(3):214-219. doi:10.1177/1753193409352410}

ArthroFLEX<sup>®</sup> Decellularized Dermal Allograft

ArthroFLEX^® Decellularized Dermal Allograft

ArthroFlex dermal allograft is an acellular dermal extracellular matrix intended for supplemental support and covering for soft-tissue repair. MatrACELL^®* technology, a patented and validated process, renders the ArthroFlex allograft dermis acellular without compromising biomechanical or biochemical properties. This process allows the matrix to retain its growth factors, native collagen scaffold, and elastin, which are required for healing.¹ Arthroflex dermal allograft improves the strength of the repair and protects it to allow healing.^2,3MatrACELL technology removes donor DNA from the dermal matrix, ensuring a biocompatible scaffold to facilitate repair.
^References:
^{1. Moore MA, Samsell B, Wallis G.}^{Cell Tissue Bank.}^{2015;16(2):249-259. doi:10.1007/s10561-014-9467-4.}
^{2. Gilot GJ, Alvarez-Pinzon AM, Barcksdale L, Westerdahl D, Krill M, Peck E.}^Arthroscopy^{. 2015;31(8):1459-65. doi:10.1016/j.arthro.2015.02.032}
^{3. Ely EE, Figueroa NM, Gilot GJ.}^Orthopedics^{. 2014;37(9):608-614. doi:10.3928/01477447-20140825-05}
*ArthroFlex and MatrACELL are registered trademarks of LifeNet Health.

Biovance<sup>®*</sup> Amniotic Membrane

Biovance^®* Amniotic Membrane

Biovance human amniotic membrane allograft serves as a natural scaffold with an intact basement membrane that has been found to support a high level of fibroblast and keratinocyte attachment.¹ Biovance amniotic membrane acts as a barrier membrane during the wound regeneration process and supports tissue growth.²
^Reference
^{1. Bhatia M, Pereira M, Rana H, et al. The mechanism of cell interaction and response on decellularized human amniotic membrane: implications in wound healing.}^Wounds^{. 2007;19(8):207-217}
^{2. Niknejad H, Peirovl H, Jorjani M, et al. Properties of the amniotic membrane for potential use in tissue engineering.}^{Eur Cell Mater}^{. 2008;15:88-99. 8}
^{*Biovance® is owned by Celularity Inc.}

CentaFlex™* Placental Matrix

CentaFlex™* Placental Matrix

CentaFlex decellularized human placental matrix allograft is derived from human umbilical cord and has the strength to support repair without the trade-off of overly thick tissue. Centaflex placental matrix serves as a cell-friendly structure to allow noninflammatory cell attachment, proliferation, and growth.
^{*CentaFlex™ is owed by Celularity Inc.}

Interfyl<sup>®*</sup>Connective Tissue Matrix

Interfyl^®*Connective Tissue Matrix

Interfyl connective tissue matrix is used to fill irregular spaces or soft-tissue deficits resulting from wounds, trauma, or surgery. Interfyl connective tissue matrix is suited for a variety of surgical applications when there is a need to replace or supplement damaged or inadequate integumental tissue.
^{*Interfyl^® is a product of Celularity Inc.}

Allograft Tendons

Allograft Tendons

Arthrex offers a variety of tendon allografts, including a wide portfolio of presutured tendons, for primary and revision ligament repairs and reconstruction procedures. Allograft tendons provide many benefits over autograft tendons in reconstructive procedures, including less donor-site morbidity,^1,2 fewer incisions, shorter operative time,^1,2 larger and predictable graft sizes,² and decreased postoperative pain and stiffness.² Arthrex offers our customers an option of sterile tendons or aseptically processed tendons. Sterile tendons from our tissue bank alliance partners are processed using methods that render the tissue sterile without causing biomechanical or biochemical changes to the tissue. Presutured constructs are an off-the-shelf solution with minimal preparation time that provide surgeons with a high-quality, consistent, sterile, and strong allograft tendon.

^References
^{1. Edgar CM Zimmer S, Kakar S, Jones H, Schepsis AA. Prospective comparison of auto and allograft hamstring tendon constructs for ACL reconstruction.}^{Clin Orthop Relat Res}^{. 2008;466(9):2238-2246. doi:10.1007/s11999-008-0305-5}
^{2. Greenberg DD, Robertson M, Vallurupalli S, White RA, Allen WC. Allograft compared with autograft infection rates in primary anterior cruciate ligament reconstruction.}^{J Bone Joint Surg Am}^{. 2010;92(14):2402-2408. doi:10.2106/JBJS.I.00456}
Disclaimer: Allograft product offerings depend on country approval and availability at LifeNet Health.

GraftNet™ Autologous Tissue Collector

GraftNet™ Autologous Tissue Collector

The suction-activated GraftNet device is designed to collect autologous tissue for a multitude of applications. When connected to an arthroscopic shaver, the GraftNet device may be used to remove tissue debris from a surgical site. This recovered autologous tissue is collected in an easily accessed, sterile filtered chamber. The GraftNet autologous tissue collector makes gaining access to autograft tissue as simple as Resect and Collect™.

TenoWrap™ Collagen Tendon Wrap

TenoWrap™ Collagen Tendon Wrap

TenoWrap™ collagen tendon wrap is a resorbable type I collagen matrix that provides a nonconstricting encasement for injured tendons and provides a protected environment and gliding surface for the tendon sheath. Designed to be an interface between the tendon and surrounding tissue, TenoWrap grafts are a conformable, nonfriable, self-curling collagen sheet for easy placement under, around, or over an injured tendon.

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