Driving innovation with the latest technological products and procedures for orthobiologics to treat a variety of conditions.

The AutoCart™ surgical technique is for the treatment of symptomatic articular cartilage defects. This surgical approach is a single-stage, matrix-augmented, autologous chondrocyte transplantation that combines articular cartilage collected using the GraftNet™ device with BioCartilage® extracellular matrix.

AutoCart™

The Angel system is the only fully automated system that utilizes 3-sensor technology (3ST) and one-button automation to prepare customized platelet-rich plasma (PRP) formulations. The Angel system has the capability to deliver platelet concentrations up to 18x baseline with adjustable leukocyte concentrations. The Angel system utilizes the principle of flow cytometry, or light absorption by cells, to achieve precise separation with reproducible results. Platelet-rich plasma may be mixed with allograft and autograft bone prior to application to an orthopedic site.
<a href="https://angelapp.arthrex.com/" class="btn btn-outline-light mb-3">Angel System Calculator Web Application</a>

Angel® System

The Arthrex ACP double-syringe system is used to facilitate the safe and rapid preparation of autologous platelet-rich plasma (PRP) from a small sample of blood at the patient’s point of care. The PRP can be mixed with autograft and allograft bone prior to application to an orthopedic surgical site as deemed necessary by the clinical use requirements. There has been increased interest in autologous blood products for use in a number of orthopedic therapies.

Arthrex ACP® Double-Syringe System

Products in this comprehensive line of AlloSync bone grafting solutions are derived from human allograft bone and maintain optimal osteoinductive and osteoconductive potential.
The comprehensive portfolio includes a wide selection of advanced demineralized bone matrix (DBM) graft options:
- AlloSync Pure demineralized bone matrix
- AlloSync Expand demineralized cortical fibers
- AlloSync demineralized cancellous sponges and cortical fibers
- AlloSync putty, gel, and paste
AlloSync products provide excellent handling characteristics and can be combined with bioactive fluids such as platelet-rich plasma (PRP) or bone marrow aspirate (BMA).

AlloSync™ Demineralized Bone Grafts

ArthroFlex dermal allograft is an acellular dermal extracellular matrix intended for supplemental support and covering for soft-tissue repair. MatrACELL®* technology, a patented and validated process, renders the ArthroFlex allograft dermis acellular without compromising biomechanical or biochemical properties. This process allows the matrix to retain its growth factors, native collagen scaffold, and elastin, which are required for healing.1 Arthroflex dermal allograft improves the strength of the repair and protects it to allow healing.2,3 MatrACELL technology removes donor DNA from the dermal matrix, ensuring a biocompatible scaffold to facilitate repair.
References:
1. Moore MA, Samsell B, Wallis G. Cell Tissue Bank. 2015;16(2):249-259. doi:10.1007/s10561-014-9467-4.
2. Gilot GJ, Alvarez-Pinzon AM, Barcksdale L, Westerdahl D, Krill M, Peck E. Arthroscopy. 2015;31(8):1459-65. doi:10.1016/j.arthro.2015.02.032
3. Ely EE, Figueroa NM, Gilot GJ. Orthopedics. 2014;37(9):608-614. doi:10.3928/01477447-20140825-05
*ArthroFlex and MatrACELL are registered trademarks of LifeNet Health.

ArthroFLEX® Decellularized Dermal Allograft

Interfyl connective tissue matrix is used to fill irregular spaces or soft-tissue deficits resulting from wounds, trauma, or surgery. Interfyl connective tissue matrix is suited for a variety of surgical applications when there is a need to replace or supplement damaged or inadequate integumental tissue.
*Interfyl® is a product of Celularity Inc.

Interfyl®*Connective Tissue Matrix

Orthobiologics

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Procedure

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The Allograft OATS instrument set facilitates harvesting of large-diameter osteochondral/hyaline cartilage cylinders from allograft bone. The core is made by placing the condyle into the workstation and harvesting with the donor harvester. A 0.5 mm-undersized recipient socket is created using the appropriately sized recipient harvester. The exact depth of the allograft to match the socket is obtained with the depth measurement guide and the allograft is trimmed to the same depth and obliquity. Dilation of the socket results in a line-to-line fit once the donor allograft is inserted into the recipient socket. Final seating of the allograft is achieved with an oversized tamp, resulting in a perfectly flush, press-fit graft that does not require fixation implants.

Allograft OATS® Set, Large

The BioPatella Instrument Set is the new standard for restoration of the articular surface of the patella when presented with oblong cartilage defects involving a significant amount of the patellar articular surface. Through a series of precisely designed cutting instruments, surgeons can replace damaged cartilage with a single, elliptical piece of viable, hyaline cartilage. The BioPatella instruments were designed to match the natural curvature of the patella to resurface the entire functional articular surface. Multiple sizes allow flexibility for the surgeon to adjust to the width and length of the cartilage defect and to ensure proper restoration of the articular surface with a single osteochondral allograft.

BioPatella™ OATS® Instrument Set

The BioUni OATS Instrument Set is the new standard for restoration of the articular surface when presented with elongated cartilage defects in the medial femoral condyle. Through a series of precisely designed cutting instruments, surgeons can replace damaged cartilage with a single, elliptical piece of viable, hyaline cartilage.

BioUni® OATS® Instrument Set

Allograft OATS®

Allograft OATS®

Secondary (C)

Knee

The disposable donor and recipient cutting tube sets of the Osteochondral Autograft Transfer System (OATS) facilitate harvesting of various diameter osteochondral/hyaline cartilage cylinders from a donor site superior and lateral to the notch or above the sulcus terminalis. A recipient socket, sized to the proper depth, is created in the chondral defect to accept the donor graft. The bone cylinder is inserted with a collared pin delivery system for press-fit fixation. Harvesting and insertion depth are controlled with 5 mm depth markings. Final seating of the harvested cylinder, flush with the surrounding articular cartilage, is achieved with a slightly larger diameter Sizer/Tamp.

Autograft OATS®

The BioACL™ technique harnesses the power of biologics to provide all necessary components of healing. In this procedure, AlloSync™ Pure demineralized bone matrix, autologous tissue collected using the GraftNet™ device, and Angel® system concentrated platelet-rich plasma from BMA delivered into the bone tunnels created during ACL reconstruction. In conjunction with the GraftLink® technique, this provides the ultimate anatomic, minimally invasive, and reproducible approach for biologically augmented ACL reconstructions.

BioACL™ Technique

BioACL ™ Technique

The IntraOsseous BioPlasty (IOBP) surgical technique is for the treatment of bone pathologies resulting from acute or chronic injury, including bone marrow lesions associated with insufficiency fractures, persistent bone bruises, osteoarthritis, and early stages of avascular necrosis. The IOBP® procedure treats these pathologies through a core decompression of the lesion and a direct application of platelet-rich plasma concentrate (cPRP) from bone marrow aspirate (BMA) using the Arthrex Angel® cPRP and bone marrow processing system. The IOBP procedure encourages physiologic bone remodeling and repair.

IntraOsseous BioPlasty® (IOBP) Technique

IntraOsseous BioPlasty® Technique

IntraOsseous BioPlasty® Technique

The segmental meniscus transplant technique addresses failed repair of the meniscus while avoiding total replacement. Patients who have irreparable defects can benefit from a partial replacement, completed using the segmental meniscus transplant technique, which provides the same tibiofemoral joint compartment biomechanics as an intact meniscus.1-3 This technique helps preserve the native biomechanical loading principles of the knee while keeping intact native hoop fibers.
References
1. Strauss E, Caborn DNM, Nyland J, Horng S, Chagnon M, Wilke D. Tissue healing following segmental meniscal allograft transplantation: a pilot study. Knee Surg Sports Traumatol Arthrosc. 2019;27(6):1931-1938. doi:10.1007/s00167-019-05355-z
2. Seiter MN, Haber DB, Ruzbarsky JJ, Arner JW, Peebles AM, Provencher MT. Segmental meniscus allograft transplantation. Arthrosc Tech. 2021;10(3):e697-e703. doi:10.1016/j.eats.2020.10.059
3. Nyland J, Campbell K, Kalloub A, Strauss EJ, Kuban K, Caborn DNM. Medial meniscus grafting restores normal tibiofemoral contact pressures. Arch Orthop Trauma Surg. 2018;138(3):361-367. doi:10.1007/s00402-017-2849-x

Segmental Meniscus Transplant

The dovetail technique simplifies graft preparation with a time-saving series of cuts preparing the bone component of the graft to sit securely in the recipient semi-trapezoidal slot created in the tibia. A matching semi-trapezoidal shaped recipient slot created in the tibia with a series of step drills, rasps and dilators matches the bone block preparation. Subsequent peripheral graft fixation to the capsular rim with 2-0 FiberWire® achieves the goal of creating a solid meniscal allograft construct. Preferably performed for lateral meniscal incompetence, the dovetail technique anatomically recreates the normal lateral meniscal relationships within the knee.

Dovetail/Slot Meniscal Transplant Technique

The Double Bone Plug technique for meniscal tear/deficiency utilizes bone plugs that can either be prepared freehand or by using a coring reamer. The freehand technique is performed using rongeurs and a high speed burr. For detailed information about this technique and/or Arthrex products utilized in this technique, visit the educational resources tab or products tab below. The double bone plug technique for meniscal allograft reconstruction provides a method for implanting the meniscal allograft medially with rigid fixation at both horn attachments. It has been demonstrated that bony fixation and bony healing at the attachment site allows for the maintenance of functional hoop stress by the meniscal allograft.

Double Bone Plug Meniscal Transplant

Soft-tissue meniscal allograft transplantation techniques continue to evolve with the advancement of fixation devices. Using common meniscal repair devices allows for greater flexibility while ensuring anatomic graft placement. Soft–tissue-only meniscal allograft surgical techniques and clinical outcomes are well documented and have good clinical efficacy.1-4
References
1. Kim SH, Lipinski L, Pujol N. Meniscal allograft transplantation with soft-tissue fixation including the anterior intermeniscal ligament. Arthrosc Tech. 2019;9(1):e137-e142. doi:10.1016/j.eats.2019.09.015
2. Spalding T, Parkinson B, Smith NA, Verdonk P. Arthroscopic meniscal allograft transplantation with soft-tissue fixation through bone tunnels. Arthrosc Tech. 2015;4(5):e559-e563. doi:10.1016/j.eats.2015.06.001
3. Elattar M, Dhollander A, Verdonk R, Almqvist KF, Verdonk P. Twenty-six years of meniscal allograft transplantation: is it still experimental? A meta-analysis of 44 trials. Knee Surg Sports Traumatol Arthrosc. 2011;19(2):147-157. doi:10.1007/s00167-010-1351-6
4. Myers P, Tudor F. Meniscal allograft transplantation: how should we be doing it? A systematic review. Arthroscopy. 2015;31(5):911-925. doi:10.1016/j.arthro.2014.11.020

Orthobiologics

AutoCart™

AutoCart™

Allograft OATS®

Autograft OATS^®

BioACL™ Technique

IntraOsseous BioPlasty® Technique

Meniscus Transplantation

Disclaimers

Disclaimers

What's New in Orthobiologics

Orthobiologics

AutoCart™

AutoCart™

Allograft OATS®chevron_right

Autograft OATS®

BioACL™ Technique

IntraOsseous BioPlasty® Technique

Meniscus Transplantationchevron_right

Disclaimers

Disclaimers

What's New in Orthobiologics

Allograft OATS®

Autograft OATS^®

Meniscus Transplantation