Biologics

AlloSync™ Bone Grafting Solutions
AlloSync™ Bone Grafting Solutions
The AlloSync bone grafting solutions line is a comprehensive offering of advanced DBMs for various bone grafting needs. AlloSync bone grafts contain osteoconductive and osteoinductive properties, providing the optimal signaling and scaffold for bone remodeling.
The unique geometry of AlloSync Expand 100% demineralized bone is ideal for intraoperative handling and controlled expansion into bone voids. AlloSync Expand fibers come preloaded in a syringe that allows for consistent hydration of the graft with biologic fluids, such as bone marrow aspirate (BMA).
AlloSync Pure DBM is derived from 100% demineralized cortical bone with no extrinsic carriers. When prepared, AlloSync Pure DBM will resist irrigation and can be used in a fluid environment. The clinician can control the handling properties of AlloSync Pure DBM, including decreasing viscosity of for injectable applications or increasing viscosity to add autograft bone. AlloSync bone grafts can be hydrated with fluids including platelet-rich plasma or concentrated BMA.
AlloSync™ Pure Demineralized Bone Matrix
AlloSync™ Pure Demineralized Bone Matrix
AlloSync™ Pure DBM is an osteoinductive demineralized bone matrix (DBM) derived from 100% human allograft bone. With zero extrinsic carriers, AlloSync Pure DBM maintains exceptional handling characteristics and can hold its shape in arthroscopic fluid environments. In addition to preserving the native bone's morphogenetic proteins and growth factors during the demineralization process, AlloSync Pure DBM can be hydrated with bioactive fluids like platelet-rich plasma (PRP) and concentrated PRP (cPRP) from bone marrow aspirate (BMA) for maximum bone grafting potential.
AlloSync™ Expand Demineralized Cortical Fibers
AlloSync™ Expand Demineralized Cortical Fibers
AlloSync Expand fibers are 100% demineralized bone that provide controlled expansion into bone voids to improve bone gap fill. A unique geometry and structure give way to the fibers' excellent handling characteristics and the preservation of the demineralized bone's osteoinductive potential. AlloSync Expand fibers may be hydrated with bone marrow, blood, and other physiological fluids to create a cellular bone graft solution for bone voids.
AlloSync™ Strips, Chips, Fibers, and Cubes
AlloSync™ Strips, Chips, Fibers, and Cubes
AlloSync bone grafting solutions maintain optimal osteoconductive potential and can be combined with bioactive fluids like platelet-rich plasma (PRP) or Angel(r) concentrated PRP (cPRP) from bone marrow aspirate. AlloSync bone grafts are derived from human allograft bone and provide excellent handling characteristics in intraoperative settings.


The portfolio of AlloSync putty, strips, and chips includes a wide selection of advanced demineralized bone matrix (DBM) graft options:
ArthroCell™ Viable Bone
ArthroCell™ Viable Bone
Arthrocell is a viable bone allograft that contains cellular, scaffold, and gel components derived from human bone. The microparticulate scaffold is comprised of a proprietary blend of cortical and cancellous allograft bone. The bone-derived gel component provides optimal handling and resists irrigation. The cellular component consists of mesenchymal stem cells (MSCs), osteoprogenitor cells and pluripotent cells.
BioSurge™ Cell and Bone Graft Processing System
BioSurge™ Cell and Bone Graft Processing System
The BioSurge™ cell and bone graft processing system combines the matrices of the AlloSync™ bone grafting solutions line with the Angel® system’s proprietary technology to prepare customized platelet-rich plasma concentrate (cPRP) from bone marrow aspirate (BMA). Hydrated AlloSync bone grafts provide the optimal scaffold for cPRP from BMA, which is a rich source of platelets and nucleated progenitor cells.
BoneSync™ Putty and Strips
BoneSync™ Putty and Strips
The BoneSync™ filler portfolio provides surgeons with several bone void solutions with excellent handling characteristics. These products provide an osteoconductive scaffold and can be hydrated with biologic fluids such as bone marrow aspirate to optimize bone remodeling potential.1,2
The BoneSync portfolio includes:
References
1. Cho AR, Kim HK, Kwon JY, Kim TK, Choi YM, Kim KH. Pain Physician J. 2014;17(6):E737-E745.
2. Chen JC, Ko CL, Shih CJ, Tien YC, Chen WC. J Dent. 2012;40(2):114-122. doi: 10.1016/j.jdent.2011.11.003.
BoneSync™ BioActive Synthetic Bone Void Filler
BoneSync™ BioActive Synthetic Bone Void Filler
BoneSync™ BioActive is a second-generation synthetic bone void filler that elicits osteoconductivity and osteostimulative potential, allowing for bony ingrowth across a fracture or fusion site.1 Comprised of a sophisticated trio of components that includes bioactive glass, BoneSync BioActive filler provides healing benefits to patients and is available in a variety of sizes in strip and putty forms.


Reference
1. Xynos ID, Hukkanen MV, Batten JJ, Buttery LD, Hench LL, Polak JM. Bioglass 45S5 stimulates osteoblast turnover and enhances bone formation In vitro: implications and applications for bone tissue engineering. Calcif Tissue Int. 2000;67(4):321-9. doi:1.1007/s002230001134
OsteoAuger™ Bone Graft Harvesting System
OsteoAuger™ Bone Graft Harvesting System
The OsteoAuger™ Bone Graft Harvesting System provides surgeons with an efficient way to recover autogenous, morselized bone from various harvest sites including the calcaneus, distal and proximal tibia, iliac crest, and distal radius. These harvesters are sterile, single-use systems that are available in diameters of 6 mm, 8 mm, and 10 mm. The autogenous morselized bone can be packed into fusion or fracture sites to enhance bone healing and remodeling.
GraftNet™ Autologous Tissue Collector
GraftNet™ Autologous Tissue Collector
The suction-activated GraftNet device is designed to collect autologous tissue for a multitude of applications. When connected to an arthroscopic shaver, the GraftNet device may be used to remove tissue debris from a surgical site. This recovered autologous tissue is collected in an easily accessed, sterile filtered chamber. The GraftNet autologous tissue collector makes gaining access to autograft tissue as simple as Resect and Collect™.
Angel<sup>®</sup> cPRP and Bone Marrow Processing System
Angel® cPRP and Bone Marrow Processing System
The Angel cPRP and bone marrow processing system uses a proprietary platelet sensor and 1-button automation to deliver customized platelet-rich plasma (PRP) concentrate from bone marrow aspirate (BMA). Bone marrow is a rich source of platelets and nucleated progenitor cells. The Angel device is the only one to provide PRP concentrate from BMA with adjustable cellular levels.
Spine Vortex™ Threaded Recovery Needles
Spine Vortex™ Threaded Recovery Needles
The Vortex™ threaded recovery needle is ideal for maximizing the concentration of osteoprogenitor cells harvested during bone marrow aspiration.1 The unique designs of the threaded tip and vent holes allow the user to easily and accurately reposition the tip of the needle within the bone for optimal aspiration volume.
Patent pending
Reference
1. McLain RF, Boehm CA, Rufo-Smith C, Muschler GF. Transpedicular aspiration of osteoprogenitor cells from the vertebral body: progenitor cell concentrations affected by serial aspiration. Spine J. 2009;9(12):995-100
Arthrex ACP<sup>®</sup> Double-Syringe System
Arthrex ACP® Double-Syringe System
The Arthrex ACP double-syringe system is used to facilitate the safe and rapid preparation of autologous platelet-rich plasma (PRP) from a small sample of blood at the patient’s point of care. The PRP can be mixed with autograft and allograft bone prior to application to an orthopedic surgical site as deemed necessary by the clinical use requirements. There has been increased interest in autologous blood products for use in a number of orthopedic therapies.
ACP Max™ PRP System
ACP Max™ PRP System
The ACP Max™ system allows for collection of 30 mL, 60 mL, or 90 mL of whole blood for the preparation of platelet-rich plasma (PRP). Using a double-spin regimen, this buffy–coat-based system creates a PRP solution depleted of red blood cells and granulocytes, including neutrophils.1 Additional whole blood in the ACP Max PRP system encourages a more concentrated PRP solution and has the capability to create platelet concentrations up to 12 times higher than whole blood alone.1


Reference
1. Arthrex, Inc. Data on file (APT-5535). Naples, FL; 2022.
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