Name: Arthrex Amnion™ Matrix Science and Applications
Uploaded: 2017-06-21T00:00:00Z
Channel: Arthrex

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VID1-00794-EN | A | Arthrex Amnion™ Matrix Science and Applications

Christopher Adams

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Thomas Temple

A video recording of a panel discussion with a surgeon along with either a product manager, a medical education team member, or other surgeons.

Videoaufzeichnung einer Podiumsdiskussion mit einem Chirurgen oder Chirurgin zusammen mit entweder einem Produktmanager oder Produktmanagerin, einem Mitglied des Medical Education-Teams oder anderen Chirurg:innen.

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Vídeo de um painel de discussão com um cirurgião, juntamente com um gerente de produto, um membro da equipe de educação médica ou outros cirurgiões.

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Video de panel de discusión con un cirujano junto con un gerente de producto, un miembro del equipo de educación médica u otros cirujanos.

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Arthrex Amnion™ Matrix Science and Applications

Today we're going to be talking about amnion and its applications in orthopedics. Joining us is Doctor Thomas Temple, a board certified fellowship trained orthopedic surgeon in orthopedic oncology from Nova Southeastern University. Tom, thank you for joining us today. Thank you for having me. So what is amnion and what makes this allograft tissue so intriguing for use in orthopedic applications? Amnion is really a product of two basic components the amniotic layer and the chorion. Both make up the amniotic sac. Amnion is very important because it's a barrier film. Moreover, it has significant growth and anti-inflammatory properties so that it has great applications in orthopedic surgery to treat degenerative conditions, trauma, and other conditions that require considerable repair and regenerative aspects. Could you share with us any tips or pearls you have for preparing this allograft for implantation? It's really important to consider what amnion product you're using. For example, the amnion layer is quite thin. It's only 100 microns, so it's tissue thin. So that one has to use forceps and avoid touching it with any wet object or finger. It lays very gently onto the surface that you have in mind. The cord itself is even thicker still, measuring approximately 800 microns, and it can actually hold a suture, so it's the easiest product to use. So along those lines, which procedures are you seeing amnion being used for and why? Amnion is used principally for open procedures. It's used in procedures where you're trying to reduce inflammation and encourage wound healing. But could it also be used for open tendon repair, for example Achilles tendon, posterior tibial tendon and the like? For rotator cuff, where you're doing an arthroscopic manipulation, I think that the cord is a better structural allograft because you could put a suture through it and you could do it without or with minimal manipulation. So what has been your experience in using amnion? I have found it to be very useful in affecting healing, particularly in patients who have comorbidities that mitigate normal wound healing, for example, patients with diabetes or wounds that are in unfavorable locations, like the upper medial thigh or intertriginous folds. So I found it to be quite exceptional in affecting healing in those areas. Moreover, I found it to be a very useful after extraction of a nerve sheath tumor or working on an open tendon repair to prevent adhesions and and to affect tendon gliding. So a lot of applications. But is it safe? It's quite safe. In fact, it undergoes the same scrutiny as any allogeneic tissue product. In this case, it comes from a living donor. The living donor asked the answers the same 26 page medical questionnaire. Moreover, it undergoes the same surveillance scrutiny for bacteria as well as serology to exclude the possibility of viral diseases. It's manipulated in aseptic fashion and packaged sterile and is quite easy to use. So you mentioned the donors. So where exactly are these? Where is the amnion coming from? So the tissue actually comes from healthy women at 38 weeks Gestation, and it comes from only two, simply because as the tissue passes through the birth canal, it could be contaminated, so we only require it from C-section donors. Are you aware of any obstacles to using amnion? Well, the only real obstacle. I believe, is cost and efficacy. Demonstration I think that third party payers have to become acquainted with the effectiveness of the tissue and the reliability in achieving the results that you're attempting to achieve. Now, I've heard of cellular and acellular amniotic tissue. What's the difference? In my view, there isn't a cellular amniotic tissue. The reality is, whether you're removing fluid through amniotic fluid recovery or whether you're processing membranes. Neither have cells. Now, the fluid some espoused to have amniotic stem cells. But the reality is we've never been able to recover amniotic stem cells from amniotic fluid. And of course, the membranes are processed in such a way that the cells are removed. So what happens is amniotic tissue over time. Does resorb does it incorporate? What happens? It's thought that more likely than not the amnion forms a significant barrier and more likely than not incorporates and or is replaced by host tissue. And what has your experience been on how amnion has affected the healing process in your patients? Well, I can only. Say from the specific population of patients that I deal with, of course, I use it in most foot and ankle procedures because wound healing problems are a bigger issue as well as inflammation. I've also used it in the face of soft tissue sarcoma resection, where wound breakdown is really a significant problem. In addition to the later effects such as woody indurated tissue and soft tissue scarring. So in my view, it has improved my wound healing rate, certainly in patients who have undergone radiotherapy. And it mitigates the later effects of radiation by creating a more pliable soft tissue with fewer adhesions. So a lot of great clinical applications. Absolutely. Yeah. Well, Tom, thank you once again for joining us today. Thank you very much for having me.

Arthrex Amnion™ Matrix Science and Applications

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