Orthobiologics includes a wide range of technologies that contain a biological or biochemical component. Examples include resorbable scaffolds to reinforce soft tissue, bone grafting materials, cell therapies, and biologic factors delivered through a device. The use of orthobiologic products and inclusion of biology and biochemistry in the treatment of bone and soft tissue injuries has been a growing area of interest for surgeons in many fields. Arthrex provides a complete selection of orthobiologic products for a variety of applications.

Foot and Ankle

Product

Autograft OATS (Osteochondral Autograft Transfer System) is an excellent procedure for the repair of small osteochondral defects of the knee or ankle. Surgeons concerned about possible donor site morbidity caused by leaving the donor site sockets open may now use specially designed Allograft Plugs to fill the donor site and promote natural bone healing for a complete biologic repair.

Backfill Plugs

StimuBlast® DBM provides osteoinduction and osteoconduction with optimal handling characteristics. The Reverse Phase Medium (RPM) carrier is biocompatible and allows the DBM to be moldable and packed into any defect size or shape. Due to the RPM carrier, StimuBlast DBM thickens up at body temperature and will resist irrigation.

StimuBlast™, Demineralized Bone Matrix

Bone Allograft

Human

As the demand for bone and soft tissue increases, the orthopaedic community is turning to allograft tissues as a safe and viable option to meet the needs of their patients. Securing procedure-specific allografts from high quality tissue banking resources and coordinating the graft, graft-specific instrumentation, implants, disposables and deliveries are important considerations when performing allograft tissue reconstruction procedures. Arthrex sets a new standard of excellence while providing the most complete surgical solutions available.

Secondary (C)

Articular allografts provided through Arthrex are processed as fresh allografts with viable chondrocytes. These grafts are used in resurfacing procedures in the knee, shoulder, hip, foot and ankle. Arthrex offers numerous different fresh articular allograft types to meet the needs of the patient and surgeon.

Fresh Cartilage

Talus OATS® instrumentation facilitates harvesting of small-diameter hyaline cartilage osteochondral cores from an osteochondral allograft. Through a series of precise steps with dedicated instrumentation, the surgeon can replace damaged articular cartilage defects with healthy, fresh osteochondral tissue core that matches the contour and cartilage morphology of the recipient site. There are few treatment options for patients with large, symptomatic lesions of osteoarticular surfaces in the talus. &nbsp;This technique provides a reliable outcome when restoring articular cartilage.1 

Reference
1. Bisicchia S, Rosso F, Amendola A. Osteochondral allograft of the talus. Iowa Orthop J. 2014;34:30-37.

Talus OATS® Set

Cartilage Allograft

As part of the Allograft OATS® procedure, Arthrex offers cartilage allografts for the replacement of lesions with new cartilage.

The Small Joint OATS® (Osteochondral Autograft Transfer System) Set is a single use, sterile disposable set that facilitates the identification, recipient socket preparation, and donor harvesting of a cylindrical osteochondral graft. The recipient socket is prepared with a guide pin and same-size drill bit (matched to the donor harvester for anatomic press-fit).

Autograft Distal Extremities OATS®

Bone graft is utilized as an adjunct innumerous surgical procedures for the foot and ankle. Autogenous bone graft hasbeen shown to facilitate healing in arthrodesis sites and to fill bone voids.The Bone Graft Harvester provides a safe, easy and quick way to obtain theadequate amount of bone graft needed.

Bone Graft Harvester

Cartilage Autograft

As part of the OATS® Osteochondral Autograft Transfer System procedure, Arthrex offers instrumentation to facilitate the replacement of lesions with autograft cartilage.

ArthroFLEX® is an acellular dermal extracellular matrix intended for supplemental support and covering for soft tissue repair. MATRACELL, a patented and validated process by LifeNet Health, renders the ArthroFLEX allograft dermis acellular, without compromising biomechanical or biochemical properties. This process allows the matrix to retain its growth factors, native collagen scaffold and elastin, which is required for healing. Elastin and collagen provide unparalleled strength for supplemental support and covering for soft tissue repair. MATRACELL removes donor DNA from the dermal matrix, ensuring a biocompatible scaffold to facilitate repair. An intact acellular matrix of collagen, elastin and growth factors provides a clean scaffold intended for supplemental support and covering for soft tissue repair.

ArthroFLEX® Decellularized Dermal Allograft

Use of allograft tendons for primary and revision ACL and PCL repair has gained greater acceptance among surgeons. The use of allografts reduces OR time and eliminates the risk of donor site morbidity. Other uses of allograft tendons are for the medial collateral ligament (MCL), lateral collateral ligament (LCL), elbow ligament repair, and for lateral ankle stabilization procedures. Tendons offered by Arthrex are provided sterile from our tissue bank alliance partners. The processing methods used render the tissue sterile without causing biomechanical or biochemical changes to the tissue.

Tendon Allografts

Soft Tissue Allograft

As the demand for soft tissue repair procedures increases, the orthopaedic community is turning to allograft tissues as a safe and viable option to meet the needs of their patients. Securing procedure-specific allografts from high quality tissue banking resources and coordination of the graft, graft-specific instrumentation, implants and disposables, and delivery of these elements can slow down the process, compromise the timing and increase the cost of the procedure. Arthrex eliminates the variables by delivering everything needed to perform the most advanced allograft reconstruction procedures.

Orthobiologics

Procedure

The IntraOsseous BioPlasty IOBP® technique is used to treat subchondral bone pathologies that are a result of acute or chronic injury, such as bone marrow lesions in the talus associated with persistent bone bruising or an insufficiency fracture.&nbsp;
The IOBP&nbsp;procedure encourages physiologic bone remodeling and repair through a core decompression of the lesion and a direct application of concentrated platelet-rich plasma (cPRP) from bone marrow aspirate (BMA) mixed with Allosync Pure DBM for biologic graft to support the subchondral bone.

Orthobiologics Products

Bone Allograft

Cartilage Allograft

Cartilage Autograft

Soft Tissue Allograft

IntraOsseous BioPlasty® Technique for Foot and Ankle