The Thrombinator system is designed to produce autologous serum at the point of care. This autologous serum helps improve the handling of bone grafts hydrated with platelet-rich plasma or bone marrow aspirate by activating platelets to produce a gel that serves as a binding agent for bone graft material. The Thrombinator process applies the principles of the clotting cascade to produce autologous serum without the use of harsh chemical reagents.