There is a growing interest for Autologous blood products for use in a number of orthopaedic procedures. The aim of technologies like ACP (Autologous Conditioned Plasma) is to provide a method of providing concentrated levels of beneficial growth factors for use at the point of care.
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- blood and blood products plasma platelets platelet blood platelet plasma PRP injection growth factor PRP platelet rich plasma platelet concentrate plasma rich in growth factors platelet derived growth factor proliferation angiogenesis differentiation stem cells MSC (mesenchymal stem cells) progenitor cells
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A biological therapy to osteoarthritis treatment using platelet-rich plasma
Anitua E, Sánchez M, Orive G, Padilla S.
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A Comparative Study of 2 Methods for Obtaining Platelet-Rich Plasma
Luis Blanco Jerez, BDS, MD, DDS, Faleh M. Tamimi, DDS, PhD, and Santiago Montalvo, DDS, MSc
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A Double-Blinded Placebo Randomized Controlled Trial Evaluating Short-term Efficacy of Platelet-Rich Plasma in Reducing Postoperative Pain After Arthroscopic Rotator Cuff Repair: A Pilot Study.
Alisha Hak, MD; Krishan Rajaratnam, MD; Olufemi R Ayeni, MD; Jaydeep Moro, MD; Devin Peterson, MD; Sheila Sprague, MD and Mohit Bhandari, MD
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A New Simplified Technique for Producing Platelet-Rich Plasma: A Short Technical Note
Marlovits S, Mousavi M, Gäbler C, Erdös J, Vécsei V.
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A Prospective Series of Patients with Chronic Achilles Tendinopathy Treated with Autologous-conditioned Plasma Injections Combined with Exercise and Therapeutic Ultrasonography
Victoria M. Deans, MBChB, MRCS (Eng); Alison Miller, MCSP; James Ramos, LMS, MD, PhD, FRCS (GEd), FRCS
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A prospective study of Autologous Growth Factors (AGF) in Lumbar Interbody Fusion
Louis G. Jenis MD, Robert J. Banco MD, and Brian Kwon MD
The Spine Journal
2006 -
A Randomized Clinical Trial Evaluating Plasma Rich in Growth Factors (PRGF-Endoret) Versus Hyaluronic Acid in the Short-Term Treatment of Symptomatic Knee Osteoarthritis
Mikel Sanchez, PhD; Nicolas Fiz, PhD; Juan Azofra, PhD; Jaime Usabiaga, PhD; Enmanuel A. Recalde, PhD; Antonio G. Gutierrez, PhD; Javier Albillos, PhD; Ramon Garate, PhD; Jose J. Aguirre; Sabino Padilla, PhD; Gorka Orive, PhD and Eduardo Anitua, MD
Arthroscopy: The Journal of Arthroscopic and Related Surgery
2012 -
A study to compare the efficacy of corticosteroid therapy with platelet-rich plasma therapy in recalcitrant plantar fasciitis: A preliminary report.
Shetty VD, Dhillon M, Hegde C, Jagtap P, Shetty S.
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Accelerated wound closure in neutrophil-depleted mice
Julia Dovi, Li-Ke He, Luisa A. DiPietro
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Allograft alone versus allograft with bone marrow concentrate for the healing of the instrumented posterolateral lumbar fusion
Radek Hart, MD, PhD; Martin Komzák, MD; František Okál, MD; David Náhlík, MD; Pavel Jajtner, MD, MBA; Miloš Puskeiler, MD
The Spine Journal
2013 -
An Analysis of a Rapid, Simple, and Inexpensive Technique Used to Obtain Platelet-Rich Plasma for Use in Clinical Practice
James L. Rutkowski, DMD, Joseph M. Thomas, BS, C. Larry Bering, PhD, Julie L. Speicher, Nicholas M. Radio, PhD, Douglas M. Smith, PhD, and David A. Johnson, PhD
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An exercise-based physical therapy program for patients with patellar tendinopathy after platelet-rich plasma injection
M. van Ark, I. van den Akker-Scheek, L.T.B. Meijer, J. Zwerver
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Anatomic ACL reconstruction: does the platelet-rich plasma accelerate tendon healing?
Alcindo Silva and Ricardo Sampaio
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Anterior Lumbar Interbody Fusion with Carbon Fiber Cage Loaded with Bioceramics and Platelet-Rich Plasma. An Experimental Study on Pigs
Haisheng Li, Xuenong Zou, Qingyun Xue, Niels Egund, Martin Lind, Cody Bünger
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Antimicrobial peptides from human platelets
Yi-Quan Tang, Michael R. Yeaman, and Michael E. Selsted
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Applications of Platelet-Rich Plasma in Musculoskeletal and Sports Medicine: An Evidence-Based Approach
Rosalyn T. Nguyen, MD, Joanne Borg-Stein, MD, Kelly McInnis, DO
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Arthroscopic double row cuff repair with suture-bridging and autologous conditioned plasma injection: Functional and structural results
Jean-David Werthel, MD; Alexandre Pelissier, MD; Philippe Massin, MD; Patrick Boyer, MD and Philippe Valenti, MD
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Aspiration of osteoprogenitor cells for augmenting spinal fusion: comparison of progenitor cell concentrations from the vertebral body and iliac crest
Robert F. McLain; James E. Fleming; Cynthia A. Boehm; George F. Muschler
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Autologous conditioned plasma as therapy of tendon and ligament lesions in seven horses
Georg Rindermann, Maria Cislakova, Gisela Arndt, Bianca Carstanjen
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Autologous fibrin matrices: A potential source of biological mediators that modulate tendon cell activities
Eduardo Anitua, Mikel Sanchez, Alan T. Nurden, Mar Zalduendo, Maria de la Fuente, Gorka Orive, Juan Azofra, Isabel Andia
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Autologous Growth Factor Injections in Chronic Tendinopathy: a Systematic Review
R. J. de Vos, P. L. J. van Veldhoven, M. H. Moen, A. Weir, J. L. Tol and N. Maffulli
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Autologous Platelet Gel and Fibrin Sealant Enhance the Efficacy of Total Knee Arthroplasy: Improved Range of Motion, Decreased Length of Stay and a Reduced Incidence of Arthrofibrosis
Peter A. Everts, Roger J.J. Devilee, Cornelis J. M. Oosterbos, Christine Mahoney, Maarten Schattenkerk, Johannes Knape, Andre van Zundert
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Autologous Platelet Gel and Platelet-Poor Plasma Reduce Pain with Total Shoulder Arthroplasty
Douglas Zavadil MPS CCP LCP , C. Craig Satterlee MD, Jaime Costigan RN, David Holt MA, Valerie Shostrom MS
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Autologous platelet rich plasma for arthroscopic rotator cuff repair. A pilot study
Pietro S. Randelli, Paolo Arrigoni, Paolo Cabitza, Piero Volpi and Prof. Nicola Maffulli
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Autologous platelet-rich plasma (PRP): a revolution in soft tissue sports injury management?
Omer Mei-Dan, MD; Giuseppe Lippi, MD; Mikel Sánchez, MD; Isabel Andia, MD; and Nicola Maffulli, MD, MS, PhD, FRCS(Orth)
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Autologous Platelet-Rich Plasma as an Adipocyte In Vivo Delivery System: Case Report
Bruno Azzena, Francesco Mazzoleni, Giovanni Abatangelo, Barbara Zavan and Vincenzo Vindigni
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Autologous Platelet-Rich Plasma: Effect on Sternal Healing in the Sheep Model
Ignacio Gallo, Alberto Sáenz, Edurne Artiñano, and Javier Esquide
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Autologous platelets as a source of proteins for healing and tissue regeneration
Eduardo Anitua, Isabel Andia, Bruno Ardanza, Paquita Nurden, Alan T. Nurden
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Autologous preparations rich in growth factors promote proliferation and induce VEGF and HGF production by human tendon cells in culture
Eduardo Anitua, Isabel Andí, Mikel Sanchez, Juan Azofra, Ma del Mar Zalduendo, María de la Fuente, Paquita Nurden, Alan T. Nurden
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Autologous Proliferative Therapies in Recalcitrant Lateral Epicondylitis
Tetschke Elisa, MD; Rudolf Margit, MD; Lohmann Christoph H., MD; Stärke Christian, MD
American Journal of Physical Medicine and Rehabilitation
2014 -
Bilateral Sinus Elevation Evaluating Plasma Rich in Growth Factors Technology: A Report of Five Cases
Eduardo Anitua PhD, MD, Roberto Prado PhD, Gorka Orive PhD
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Bone Marrow Aspirate Concentrate versus Platelet Rich Plasma to Enhance Osseous Integration Potential for Osteochondral Allografts
Aaron M. Stoker; Charles A. Baumann; James P. Stannard; James L. Cook
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Classification of platelet concentrates: from pure platelet-rich plasma (P-PRP) to leucocyte- and platelet-rich fibrin (L-PRF)
David M. Dohan Ehrenfest, Lars Rasmusson and Tomas Albrektsson
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Clinical and MRI Outcomes After Platelet-Rich Plasma Treatment for Knee Osteoarthritis
Brian Halpern, MD, Salma Chaudhury, MD, PhD, MRC, Scott A. Rodeo, MD, Catherine Hayter, MD, Eric Bogner, MD, Hollis G. Potter, MD, Joseph Nguyen, MPH
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Collagen-Platelet Composite Enhances Biomechanical and Histologic Healing of the Porcine Anterior Cruciate Ligament
Shilpa Joshi, Ashley Mastrangelo, Elise Magarian, Braden Fleming, Martha M. Murray
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Collagen-Platelet Composites Improve the Biomechanical Properties of Healing Anterior Cruciate Ligament Grafts in a Porcine Model
Braden C. Fleming, PhD, Kurt P. Spindler, MD, Matthew P. Palmer, Elise M. Magarian and Martha M. Murray, MD
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Combination of Intra-Articular and Intraosseous Injections of Platelet Rich Plasma for Severe Knee Osteoarthritis: A Pilot Study
Mikel Sánchez, MD; Diego Delgado, MD; Pello Sánchez, MD; Emma Muiños-López, MD; Bruno Paiva, MD; Froilán Granero-Moltó, MD; Felipe Prósper, MD; Orlando Pompei, MD; Juan Carlos Pérez, MD; Juan Azofra, MD; Sabino Padilla, MD; Nicolás Fiz, MD
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Comparison Between Hyaluronic Acid and Platelet-Rich Plasma, Intra-articular Infiltration in the Treatment of Gonarthrosis
Fabio Cerza, MD; Stefano Carnı` MD; Alessandro Carcangiu,MD; Igino Di Vavo, MD; Valerio Schiavilla, MD; Andrea Pecora,MD; Giuseppe De Biasi; Michele Ciuffreda
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Comparison of Autologous Conditioned Plasma Injection, Extracorporeal Shockwave Therapy, and Conventional Treatment for Plantar Fasciitis: A Randomized Trial
Kelvin Tai Loon Chew, Darren Leong, Cindy Y. Lin, Kay Kiat Lim, Benedict Tan
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Comparison of Growth Factor and Platelet Concentration From Commercial Platelet-Rich Plasma Separation Systems
Tiffany N. Castillo, Michael Pouliot, Hyeon Joo Kim, Jason Dragoo
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Comparison of intra-articular injections of plasma rich in growth factors (PRGF-Endoret) versus Durolane hyaluronic acid in the treatment of patients with symptomatic osteoarthritis: a randomized controlled trial
Vaquerizo V, Plasencia MÁ, Arribas I, Seijas R, Padilla S, Orive G, Anitua E.
Arthroscopy: The Journal of Arthroscopic and Related Surgery
2013
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Comparison of Magnetic Resonance Imaging Findings in Anterior Cruciate Ligament Grafts With and Without Autologous Platelet-Derived Growth Factors
Fernando Radice, M.D., Roberto Yanez, M.D., Vicente Gutidrrez, M.D., Julio Rosales, M.D., Miguel Pinedo, M.D., and Sebastian Coda, M.D.
Arthroscopy: The Journal of Arthroscopic and Related Surgery
2010 -
Comparison of Mesenchymal Stem Cells (Osteoprogenitors) Harvested from Proximal Humerus and Distal Femur During Arthroscopic Surgery
Knut Beitzel, MA, MD; Mary Beth R. McCarthy, BS; Mark P. Cote, DPT; Thomas J.S. Durant, PT; David M. Chowaniec, BS; Olga Solovyova, BS; Ryan P. Russell, MA: Robert A. ARciero, MD; and Augustus D. Mazzocca, MS, MD
Arthroscopy: The Journal of Arthroscopic and Related Surgery
2013 -
Comparison of mesenchymal stem cells from bone marrow and adipose tissue for bone regeneration in a critical size defect of the sheep tibia and the influence of platelet-rich plasma
Philipp Niemeyer, Katharina Fechner, Stefan Milz, Wiltrud Richter, Norbert Suedkamp, Alexander Mehlhorn, Simon Pearce, Philip Kasten
Biomaterials
2010
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Comparison of short-term results of intraarticular platelet-rich plasma (PRP) and hyaluronic acid treatments in early-stage gonarthrosis patients
Guler O, Mutlu S, Isyar M, Seker A, Kayaalp ME, Mahirogullari M
EJOST European Journal of Orthopaedic Surgery & Traumatology
2014 -
Comparison of Surgically Repaired Achilles Tendon Tears Using Platelet-Rich Fibrin Matrices
Mikel Sánchez, Eduardo Anitua, Juan Azofra, Isabel Andía, Sabino Padilla and Iñigo Mujika
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Correlation of Platelet Concentration in Platelet-rich Plasma to the Extraction Method, Age, Sex, and Platelet Count of the Donor
Gernot Weibrich, MD, DDS, Wilfried Kleis, MD, Marika Kunz-Kostomanolakis, MD, Anja Loos, Wilfried Wagner, MD DDS Prof
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Corticosteroids and local anesthetics decrease positive effects of platelet-rich plasma: an in vitro study on human tendon cells
Carofino B, Chowaniec DM, McCarthy MB, Bradley JP, Delaronde S, Beitzel K, Cote MP, Arciero RA, Mazzocca AD
Arthroscopy: The Journal of Arthroscopic and Related Surgery
2012 -
CT-Guided Bone Biopsy With a Battery-Powered Drill System: Preliminary Results
Lee RK; Ng AW; Griffith JF.
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Delivering growth factors for therapeutics
Eduardo Anitua, Mikel Sanchez, Gorka Orive, Isabel Andia
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Differential Injury Responses in Oral Mucosal and Cutaneous Wounds
A.M. Szpaderska, J.D. Zuckerman, L.A. DiPietro
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Do Autologous Growth Factors Enhance Transforaminal Lumbar Interbody Fusion?
Hwan T. Hee, Mohammed E. Majd, Richard T. Holt and Leann Myers
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Does intra articular platelet rich plasma injection improve function, pain and quality of life in patients with osteoarthritis of the knee? A randomized clinical trial.
Seyed Mansoor Rayegani, MD; Seyed Ahmad Raeissadat, MD; Morteza Sanei Taheri, MD; Marzieh Babaee, MD; Mohammad Hassan Bahrami, MD; Dariush Eliaspour, MD and Elham Ghorbani, MD
Orthopedic Reviews
2014
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Does Platelet-Rich Plasma Accelerate Recovery After Rotator Cuff Repair? A Prospective Cohort Study
Chris Hyunchul Jo, MD, Ji Eun Kim, MS, Kang Sup Yoon, MD, Ji Ho Lee, MD, Seung Baik Kang, MD, Jae Hyup Lee, MD, Hyuk Soo Han, MD, Seung Hwan Rhee, MD and Sue Shin, MD
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Does platelet-rich plasma enhance microfracture treatment for chronic focal chondral defects? An in-vivo study performed in a rat model
Hapa O, Cakıcı H, Yüksel HY, Fırat T, Kükner A, Aygün H.
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Does single intramuscular application of autologous conditioned plasma influence systemic circulating growth factors?
Schippinger G, Fankhauser F, Oettl K, Spirk S, Hofmann P
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Effect of Bupivacaine on Cultured Tenocytes
Michael B. Scherb, MD; Seung-Hwan Han, MD; Jean-Paul Courneya, BS; Gregory P. Guyton, MD; Lew C. Schon, MD
Orthopedics
2009 -
Effect of Platelet Concentration in PRP on Peri-implant Bone Regeneration
Weibrich G, Hansen T, Kleis W, Buch R, Hitzler WE.
The Bone Journal
2004 -
Effect of Platelet-Rich Plasma and Porcine Dermal Collagen Graft Augmentation for Rotator Cuff Healing in a Rabbit Model
Chung SW, Song BW, Kim YH, Park KU, Oh JH.
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Effects of a Platelet Gel on Early Graft Revascularization after Anterior Cruciate Ligament Reconstruction: A Prospective, Randomized, Double-Blind, Clinical Trial
Vogrin M, Rupreht M, Dinevski D, Hašpl M, Kuhta M, Jevsek M, Knežević M, Rožman P
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Effects of Autogenous Bone Marrow Aspirate Concentrate on Radiographic Integration of Femoral Condylar Osteochondral Allografts
Lasun O. Oladeji, MD, MS; James P. Stannard, MD; Cristi R. Cook, DVM, MS; Mauricio Kfuri, MD, PhD; Brett D. Crist, MD; Matthew J. Smith, MD; James L. Cook, DVM, PhD
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Effects of Autologous Platelet-Rich Plasma on Cell Viability and Collagen Synthesis in Injured Human Anterior Cruciate Ligament
Louay Fallouh MD PhD, Koichi Nakagawa MD PhD, Takahisa Sasho MD PhD , Momoko Arai MD, Sota Kitahara MD PhD, Yuichi Wada MD PhD, Hideshige Moriya MD PhD, Kazuhisa Takahashi MD PhD
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Effects of Platelet Concentrate and a Bone Plug on the Healing of Hamstring Tendons in a Bone Tunnel
Mario Orrego MD, Catalina Larrain MD, Juan Rosales MD, Luis Valenzuela MD, Jose Matas MD, Juan Durruty MD, Hernan Sudy MD, and Rodrigo Mardones MD
Arthroscopy: The Journal of Arthroscopic and Related Surgery
2008 -
Effects of Platelet-Rich Fibrin Matrix on Repair Integrity of At-Risk Rotator Cuff Tears
Bergeson AG, Tashjian RZ, Greis PE, Crim J, Stoddard GJ, Burks RT.
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Effects of Platelet-Rich Plasma Composition on Anabolic and Catabolic Activities in Equine Cartilage and Meniscal Explants
John D. Kisiday; C. Wayne McIlwraith; William G. Rodkey; David D. Frisbie; J. Richard Steadman
Cartilage
2012
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Effects of Repetitive Platelet-rich Plasma Application on Human Tenocyte Proliferation
Augustus D. Mazzocca, MS, MD; Knut Beitzel, MD; Mary Beth R. McCarthy, BS; David M. Chowaniec, BS; Mark P. Cote, DPT; James P. Bradley, MD; Anthony Romeo, MD; Robert A. Arciero, MD
Orthopedics
2015 -
Efficacy and safety profile of a compound composed of platelet-rich plasma and hyaluronic acid in the treatment for knee osteoarthritis (preliminary results)
Michele Abate; Sandra Verna; Cosima Schiavone; Patrizia Di Gregorio; Vincenzo Salini
EJOST European Journal of Orthopaedic Surgery & Traumatology
2015 -
Efficacy of Autologous Growth Factors in Lumbar Intertransverse Fusions
Bradley K. Weiner, MD and Matthew Walker, MD
The Spine Journal
2003
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Efficacy of Epidural Perineural Injections with Autologous Conditioned Serum for Lumbar Radicular Compression
Cordelia Becker MD, Stefan Heidersdorf MD, Sascha Drewlo MSc, Sonje Zirke de Rodriguez, Juergen Krämer MD, Roland Ernst Willburger MD
The Spine Journal
2007 -
Efficacy of intra-tendinous injection of platelet-rich plasma in treating tendinosis: comprehensive assessment of a rat model
Dallaudière B, Lempicki M, Pesquer L, Louedec L, Preux PM, Meyer P, Hummel V, Larbi A, Deschamps L, Journe C, Hess A, Silvestre A, Sargos P, Loriaut P, Boyer P, Schouman-Claeys E, Michel JB, Serfaty JM.
European Radiology
2013 -
Efficacy of Platelet-Rich Plasma for Chronic Tennis Elbow A Double-Blind, Prospective, Multicenter, Controlled Trial of 230 Patients
Allan K. Mishra, MD; Nebojsa V. Skrepnik, MD, PhD; Scott G. Edwards, MD; Grant L. Jones, MD; Steven Sampson, DO; Doug A. Vermillion, MD; Matthew L. Ramsey, MD; David C. Karli, MD and Arthur C. Rettig, MD
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Efficacy of platelet-rich plasma injections for chronic medial epicondylitis
Glanzmann MC, M.D., Audigé L, M.D.
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Efficacy of platelet-rich-plasma (PRP) in bone regeneration after cyst enucleation in pediatric patients--a clinical study
Nagaveni NB, Praveen RB, Umashankar KV, Pranav B, Sreedevi R, Radhika NB
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Emerging techniques in orthopaedics: platelet-rich plasma
Mary Atkinson Smith and W. Todd Smith
Orthopaedic Nursing
2011 -
Enhancement of Syndesmotic Fusion Rates in Total Ankle Arthroplasty with the Use of Autologous Platelet Concentrate
Craig R. Barrow, M.D.; Gregory C. Pomeroy
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Evaluation of Implant Osseointegration with Different Regeneration Techniques in the Treatment of Bone Defects Around Implants: An Experimental Study in a Rabbit Model
Isabel Guerra, Fernando Morais Branco, Mario Vasconcelos, Americo Afonso, Helena Figueiral, Raquel Zita
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Evaluation of the effects of platelet-rich plasma (PRP) therapy involved in the healing of sports-related soft tissue injuries
Middleton KK, Barro V, Muller B, Terada S, Fu FH
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Exogenous Application of Platelet-Leukocyte Gel during Open Subacromial Decompression Contributes to Improved Patient Outcome: A Prospective Randomized Double-Blind Study
Peter A. Everts, PhD and R.J.J. Devileeb, C. Brown Mahoneye, A. van Erpb, C.J.M. Oosterbosb, M. Stellenboomb, J.T.A. Knaped, A. van Zundertc
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Fibroblastic Response to Treatment with Different Preparations Rich in Growth Factors
Anitua E, Sánchez M, Zalduendo MM, de la Fuente M, Prado R, Orive G, Andía I.
Cell Proliferation
2009
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First Clinical Experience with a New Injectable Recombinant Human Collagen Scaffold Combined with Autologous Platelet-Rich Plasma for the Treatment of Lateral Epicondylar Tendinopathy (Tennis Elbow)
Uri Farkash, M.D.; Uri Farkash, M.D.; Erez Avisar, M.D.; Ido Volk, M.D.; Omer Slevin, M.D.; Noam Shohat, M.D.; Madi El Haj, M.D.; Eran Dolev, M.D.; Eran Ashraf, M.D.; Shai Luria, M.D.;
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Growth factor and catabolic cytokine concentrations are influenced by the cellular composition of platelet rich plasma
Emily A. Sundman; Brian J. Cole MD, MBA ; Lisa A. Fortier, DVM, PhD
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Growth factor delivery methods in the management of sports injuries: the state of play
L Creaney and B Hamilton
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Has Platelet-Rich Plasma Any Role in Anterior Cruciate Ligament Allograft Healing?
Juan Ramon Valenti Nin, MD PhD; Gonzalo Gasque MD PhD; Andres Valenti Azcárate MD; Jesus Beola MD; Milagros Hernandez Gonzalez MD PhD
Arthroscopy: The Journal of Arthroscopic and Related Surgery
2009 -
Immunosuppression with FK506 Increases Bone Induction in Demineralized Isogeneic and Xenogeneic Bone Matrix in the Rat
Gregor Voggenreiter, Stefan Assenmacher, Ernst Kreuzfelder, Markus Wolf, Mi-Ran Kim, Dieter Nast-Kolb, Fritz Ulrich Schade
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In vitro evaluation of the anti-bacterial effect of two preparations of platelet rich plasma compared with cefazolin and whole blood
Jessica Intravia, MD; Donald A. Allen; Thomas J. Durant, PT; Mary Beth McCarthy, BS; Ryan Russell, PhD; Knut Beitzel, MD, MA; Mark P. Cote, MS DPT; Feliciano Dias; Augustus D. Mazzocca, MD
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In Vitro Exposure to 0.5% Bupivacaine Is Cytotoxic to Bovine Articular Chondrocytes
Nicole E. Papas, B.S., Constance R. Chu, M.D. Freddie H. Fu, M.D. Nicholas J. Izzo, Ph.D.,
Arthroscopy: The Journal of Arthroscopic and Related Surgery
2006 -
Increasing Platelet Concentrations in Leukocyte-Reduced Platelet-Rich Plasma Decrease Collagen Gene Synthesis in Tendons.
Boswell SG, Schnabel LV, Mohammed HO, Sundman EA, Minas T, Fortier LA.
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Inflammatory cells during wound repair: the good, the bad and the ugly
Paul Martin and S. Joseph Leibovich
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Influence of intramuscular application of autologous conditioned plasma on systemic circulating IGF-1
Gert Schippinger, Karl Oettl, Florian Fankhauser, Stefan Spirk, Wolfgang Domej and Peter Hofmann
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Injection of Platelet-Rich Plasma in Patients with Primary and Secondary Knee Osteoarthritis
Steven Sampson DO, Marty Reed MD, Holly Silvers MPT, Michael Meng DC, Bert Mandelbaum MD
American Journal of Physical Medicine and Rehabilitation
2010 -
Injection Techniques of Platelet-Rich Plasma Into and Around the Achilles Tendon: A Cadaveric Study
C. Niek van Dijk, MD, PhD, Gino M. Kerkhoffs, MD, PhD, Johannes I. Wiegerinck, MSc, Milko C. de Jonge, MD, Mikel L. Reilingh, MD
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Intervertebral Disc Regeneration Using Platelet-Rich Plasma and Biodegradable Gelatin Hydrogel Microspheres
Nagae M, Ikeda T, Mikami Y, Hase H, Ozawa H, Matsuda K, Sakamoto H, Tabata Y, Kawata M, Kubo T.
Tissue Engineering
2007 -
Intraarticular Administration of Platelet-Rich Plasma with Biodegradable Gelatin Hydrogel Microspheres Prevents Osteoarthritis Progression in the Rabbit Knee
Saito M, Takahashi KA, Arai Y, Inoue A, Sakao K, Tonomura H, Honjo K, Nakagawa S, Inoue H, Tabata Y, Kubo T.
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Intra-articular injection of an autologous preparation rich in growth factors for the treatment of knee OA: a retrospective cohort study
M. Sanchez, E. Anitua, J. Azofra, J.J. Aguirre and I. Andia
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Intraoperative Use of Autologous Platelet-Rich and Platelet-Poor Plasma for Orthopedic Surgery Patients
Kathleen M. Floryan, RN and William J. Berghoff, MD
AORN Journal
2004 -
Lidocaine Exhibits Dose-and-Time-Dependent Cytotoxic Effects on Bovine Articular Chondrocytes In Vitro
John C. Karpie and Constance R. Chu
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Ligamentization of Tendon Grafts Treated With an Endogenous Preparation Rich in Growth Factors: Gross Morphology and Histology
Mikel Sánchez MD, Eduardo Anitua MD, Juan Azofra MD, Roberto Prado PhD, Francisco Muruzabal PhD, and Isabel Andia PhD
Arthroscopy: The Journal of Arthroscopic and Related Surgery
2010 -
Magnetic Resonance Imaging Evaluation of the Integration and Maturation of Semitendinosus-Gracilis Graft in Anterior Cruciate Ligament Reconstruction Using Autologous Platelet Concentrate
Patricio Melean MD, Rafael Calvo MD, Alex Vaisman MD, Nicolas Zilleruelo MD, Ignacio Villalón MD, David Figueroa, M.D. and Francisco Figueroa MD
Arthroscopy: The Journal of Arthroscopic and Related Surgery
2006 -
Meniscal repair using an exogenous fibrin clot. An experimental study in dogs
Arnoczky SP, Warren RF, Spivak JM.
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Mesenchymal Stem Cell Implantation in Knee Osteoarthritis: An Assessment of the Factors Influencing Clinical Outcomes
Yong Sang Kim, MD; Yun Jin Choi, MD; Yong Gon Koh, MD
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Neutrophil Infiltration in Exercise-Injured Skeletal Muscle: How Do We Resolve the Controversy?
Barbara St. Pierre Schneider and Peter M. Tiidus
Sports Medicine
2007 -
New insights into and novel applications for platelet-rich fibrin therapies
Eduardo Anitua, Mikel Sanchez, Paquita Nurden, Gorka Orive, Isabel Andia, Alan Nurden
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Nonunions Treated With Autologous Preparation Rich in Growth Factors
Isabel Andia, M. Sanchez, E. Anitua, R. Cugat, J. Azofra, J. Guadilla, R. Seijas
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One-Year Follow-up of Platelet-Rich Plasma Treatment in Chronic Achilles Tendinopathy A Double-Blind Randomized Placebo-Controlled Trial
Suzan de Jonge, MD, Robert J. de Vos, MD, PhD, Adam Weir, MD, Hans T. M. van Schie, DVM, PhD, Sita M. A. Bierma-Zeinstra, PhD, Jan A. N. Verhaar, MD, PhD, Harrie Weinans, PhD and Johannes L. Tol, MD, PhD
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Ongoing Positive Effect of Platelet-Rich Plasma Versus Corticosteroid Injection in Lateral Epicondylitis A Double-Blind Randomized Controlled Trial With 2-year Follow-up
Taco Gosens, MD, PhD, Joost C. Peerbooms, MD, Wilbert van Laar and Brenda L. den Oudsten, PhD
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Optimization of Leukocyte Concentration in Platelet-Rich Plasma for the Treatment of Tendinopathy
Taralyn M. McCarrel, DVM, Tom inas, MD, MS, and Lisa A. Fortier, DVM, PhD
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Partial Regeneration of the Human Hip Via Autologous Bone Marrow Nucleated Cell Transfer: A Case Study
Christopher J Centeno, MD, John Kisiday, PhD, Michael Freeman, PhD, and John R Schultz, MD
Pain Physician
2006 -
Patellar Tendon Healing With Platelet-Rich Plasma: A Prospective Randomized Controlled Trial
Adriano Marques de Almeida, MD, MS; Marco Kawamura Demange, MD, PhD; Marcel Faraco Sobrado; Marcelo Bordalo Rodrigues, MD; André Pedrinelli, MD, PhD and Arnaldo José Hernandez, MD, PhD
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Percutaneous Autologous Bone-Marrow Grafting for Nonunions: Influence of the Number and Concentration of Progenitor Cells
Ph. Hernigou, MD; A. Poignard, MD; F. Beaujean, MD; H. Rouard, MD
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Plasma rich in growth factors (PRGF-Endoret) stimulates corneal wound healing and reduces haze formation after PRK surgery
Anitua E, Muruzabal F, Alcalde I, Merayo-Lloves J, Orive G.
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Plasma rich in growth factors (PRGF-Endoret) stimulates tendon and synovial fibroblasts migration and improves the biological properties of hyaluronic acid
Anitua E, Sanchez M, De la Fuente M, Zalduendo MM, Orive G.
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Plasma Rich in Growth Factors and Bone Formation: A Radiological and Histomorphometric Study in New Zealand Rabbits
Francisco Molina-Miñano, DDS and Pia López-Jornet PhD MD DDS, Fabio Camacho-Alonso PhD DDS, Vicent Vicente-Ortega PhD MD
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Plasma Rich in Growth Factors to Treat an Articular Cartilage Avulsion: A Case Report
Mikel Sanchez, Juan Azofra, Eduardo Anitua, Isabel Andia, Sabina Padilla, Juanma Santistaben, and Inigo Mujika
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Plasma rich in growth factors: The pioneering autologous technology for tissue regeneration
Eduardo Anitua, Mikel Sánchez, Roberto Prado, Gorka Orive
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Platelet activation by collagen provides sustained release of anabolic cytokines
Harrison S, Vavken P, Kevy S, Jacobson M, Zurakowski D, Murray MM.
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Platelet Concentrate Increases Bone Ingrowth into Porous Hydroxyapatite
Maikel Siebrecht, MD, Philippe De Rooij, MD, Martin Olsson, MD PhD, Per Aspenberg, MD PhD, Douglas Arm, MSc
Orthopedics
2002
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Platelet concentrate vs. saline in a rat patellar tendon healing model
Jeffrey T. Spang, Thomas Tischer, Gian Salzmann, Tobias Winkler, Rainer Burgkart, Gabriele Wexel, Andreas Imhoff
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Platelet Content and Growth Factor Release in Platelet-Rich Plasma: a Comparison of Four Different Systems
Leitner GC, Gruber R, Neumüller J, Wagner A, Kloimstein P, Höcker P, Körmöczi GF, Buchta C.
Vox Sanguinis
2006 -
Platelet Gel (AGF) Fails to Increase Fusion Rates in Instrumented Posterolateral Fusions
Leah Yacat Carreon MD, Steven Glassman MD, Yoram Anekstein MD, Rolando Puno MD
The Spine Journal
2005
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Platelet Gel and Fibrin Sealant Reduce Allogeneic Blood Transfusions in Total Knee Arthroplasty
Everts PA, Devilee RJ, Brown Mahoney C, Eeftinck-Schattenkerk M, Box HA, Knape JT, van Zundert A.
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Platelet Rich Concentrate: Basic Science and Current Clinical Applications
Samir Mehta, MD and J. Tracy Watson, MD
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Platelet rich plasma in arthroscopic rotator cuff repair: a prospective RCT study, 2-year follow-up
Pietro Randelli, MD, Paolo Arrigoni, MD, Vincenza Ragone, MEng, Alberto Aliprandi, MD, Paolo Cabitza, MD
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Platelet rich plasma injection grafts for musculoskeletal injuries: a review
Steven Sampson, Michael Gerhardt, Bert Mandelbaum
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Platelet Rich Plasma: Biology and New Technology
Barry Eppley MD DMD and William Pietrzak PhD
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Platelet-Released Growth Factors Enhance the Secretion of Hyaluronic Acid and Induce Hepatocyte Growth Factor Production by Synovial Fibroblasts from Arthritic Patients
Anitua E, Sánchez M, Nurden AT, Zalduendo MM, de la Fuente M, Azofra J, Andía I.
Rheumatology
2007
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Platelet-Rich Plasma (PRP) - What Is PRP and What Is Not PRP?
Robert Marx DDS
Implant Dentistry
2001 -
Platelet-Rich Plasma (PRP) for Acute Muscle Injury: A Systematic Review
Mohamad Shariff A. Hamid; Ashril Yusof; Mohamed Razif Mohamed Ali
PLOS one
2014 -
Platelet-rich plasma (PRP) intra-articular ultrasound-guided injections as a possible treatment for hip osteoarthritis: a pilot study
Battaglia M, Guaraldi F, Vannini F, Buscio T, Buda R, Galletti S, Giannini S
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Platelet-Rich Plasma (PRP) Stimulates the Extracellular Matrix Metabolism of Porcine Nucleus Pulposus and Anulus Fibrosus Cells Cultured in Alginate Beads
Koji Akeda MD, Howard S. An MD, Rajeswari Pichika PhD, Mohamed Attawia MD, Eugene Thonar PhD, Mary Ellen Lenz MS, Atsumasa Uchida, MD PhD, and Koichi Masuda MD
The Spine Journal
2006 -
Platelet-Rich Plasma and Platelet Gel: A Review
Peter Everts EKP ECCP, Johannes Knape MD PhD, Gernot Weibrich, MD, DDS, PhD and Jacques P.A.M. Schonberger MD PhD, Johannes Hoffmann PhD, Eddy Overdevest, EKP, ECCP, Henk A.M. Box, EKP ECCP, Andre van Zundert, MD PhD FRCA
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Platelet-Rich Plasma Application During Closure Following Total Knee Arthroplasty
William J. Berghoff, MD; William S. Pietrzak, PhD; Richard D. Rhodes, MD
Orthopedics
2006 -
Platelet-Rich Plasma as a Treatment for Patellar Tendinopathy: A Double-Blind, Randomized Controlled Trial
Dragoo JL, Wasterlain AS, Braun HJ, Nead KT.
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Platelet-rich plasma as an effective treatment for proximal hamstring injuries
Robert J. Wetzel, MD; Ronak M. Patel, MD; Michael A. Terry, MD
Orthopedics
2013
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Platelet-rich plasma augmentation for arthroscopic RC repair- a randomized controlled trial.
Castricini R, Longo UG, De Benedetto M, Panfoli N, Pirani P, Zini R, Maffulli N, Denaro V.
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Platelet-Rich Plasma Augmentation for Arthroscopic Rotator Cuff Repair: A Randomized Controlled Trial
Roberto Castricini, Umile Giuseppe Longo, Massimo De Benedetto , Nicola Panfoli, Piergeorgio Pirani, Raul Zini, Nicola Maffulli, Vincenzo Denaro
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Platelet-Rich Plasma Compared with Corticosteroid Injection for Chronic Lateral Elbow Tendinosis
Allan Mishra, MD, Herve Collado, MD and Michael Fredericson, MD
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Platelet-Rich Plasma Differs According to Preparation Method and Human Variability
Augustus D. Mazzocca, MS, MD; Mary Beth R. McCarthy, BS; David M. Chowaniec, BS; Mark P. Cote, DPT; Anthony A. Romeo, MD; James P. Bradley, MD; Robert A. Arciero, MD; Knut Beitzel, MD
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Platelet-Rich Plasma for Arthroscopic Repair of Large to Massive Rotator Cuff Tears A Randomized, Single-Blind, Parallel-Group Trial
Chris Hyunchul Jo, MD; Ji Sun Shin, BS; Young Gil Lee, MD; Won Hyoung Shin, MD; Hyang Kim, PhD; Seung Yeon Lee, MS; Kang Sup Yoon, MD and Sue Shin, MD
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Platelet-rich Plasma for Articular Cartilage Repair
Geoffrey D. Abrams, MD; Rachel M.Frank, MD; Lisa A. Fortier, DVM, PhD; Brian J. Cole, MD, MBA
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Platelet-rich plasma for foot and ankle pathologies: A systematic review
F. Vannini, B. Di Matteo, G. Filardo, E. Kon, M. Marcacci, S. Giannini
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Platelet-rich Plasma for Muscle Injury and Tendinopathy
Andia I, Maffulli N.
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Platelet-rich plasma for the treatment of patellar tendinopathy: clinical and imaging findings at medium-term follow-up
Filardo G, Kon E, Di Matteo B, Pelotti P, Di Martino A, Marcacci M.
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Platelet-rich plasma gel promotes regeneration of articular cartilage in knees of sheeps
Márcio de Oliveira Carneiro, Cláudio Henrique Barbieri, and José Barbieri, Neto
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Platelet-Rich Plasma in Muscle Healing
Borrione P, Gianfrancesco AD, Pereira MT, Pigozzi F.
American Journal of Physical Medicine and Rehabilitation
2010 -
Platelet-rich plasma in patients with tibiofemoral cartilage degeneration
Hart R, Safi A, Komzák M, Jajtner P, Puskeiler M, Hartová P.
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Platelet-Rich Plasma in Rotator Cuff Repair A Prospective Randomized Study
Eduardo Angeli Malavolta, PhD; Mauro Emilio Conforto Gracitelli, MD; Arnaldo Amado Ferreira Neto, PhD; Jorge Henrique Assunção, MD; Marcelo Bordalo-Rodrigues, MD and Olavo Pires de Camargo, PhD
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Platelet-Rich Plasma in the Management of Articular Cartilage Pathology: A Systematic Review
Dold AP, Zywiel MG, Taylor DW, Dwyer T, Theodoropoulos J.
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Platelet-Rich Plasma in the Pathologic Processes of Cartilage: Review of Basic Science Evidence
Niall A. Smyth, MD; Christopher D. Murawski, BS; Lisa A. Fortier, DVM, PhD; Brian J. Cole, MD, MBA; and John G. Kennedy, MD, FRCS
Arthroscopy: The Journal of Arthroscopic and Related Surgery
2013 -
Platelet-Rich Plasma Injection for Chronic Achilles Tendinopathy
Robert de Vos MD, Adam Weir MBBS, Hans van Schie DVM, PhD, Sita Bierma-Zeinstra PhD, Jan Verhaar MD PhD, Harrie Weinans PhD, Johannes Tol MD PhD
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Platelet-Rich Plasma Injection Reduces Pain in Patients With Recalcitrant Epicondylitis
Keith S. Hechtman, MD; John W. Uribe, MD; Angie Botto-vanDemden, PhD; Gary M. Kiebzak, PhD
Orthopedics
2011 -
Platelet-rich plasma injections for chronic plantar fasciitis
Nicolo Martinelli; Andrea Marinozzi; Stefano Carnì; Ugo Trovato; Alberto Bianchi; Vincenzo Denaro
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Platelet-Rich Plasma Injections in the Treatment of Chronic Rotator Cuff Tendinopathy A Randomized Controlled Trial With 1-Year Follow-up
Serdar Kesikburun, MD; Arif Kenan Tan, MD; Bilge Yılmaz, MD; Evren Yaşar, MD and Kamil Yazıcıoğlu, MD
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Platelet-rich plasma intra-articular injection versus hyaluronic acid viscosupplementation as treatments for cartilage pathology: from early degeneration to osteoarthritis
Kon E, Mandelbaum B, Buda R, Filardo G, Delcogliano M, Timoncini A, Fornasari PM, Giannini S, Marcacci M.
Arthroscopy: The Journal of Arthroscopic and Related Surgery
2011 -
Platelet-rich plasma intra-articular injections for cartilage degeneration and osteoarthritis: single- versus double-spinning approach
Filardo G, Kon E, Pereira Ruiz MT, Vaccaro F, Guitaldi R, Di Martino A, Cenacchi A, Fornasari PM, Marcacci M.
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Platelet-rich plasma intra-articular knee injections for the treatment of degenerative cartilage lesions and osteoarthritis
Filardo G, Kon E, Buda R, Timoncini A, Di Martino A, Cenacchi A, Fornasari PM, Giannini S, Marcacci M
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Platelet-Rich Plasma on Calcium Phosphate Granules Promotes Metaphyseal Bone Healing in Mini-Pigs
Pascal Jungbluth, Michael Wild, Jan-Peter Grassmann, Ebru Ar, Martin Sager, Monika Herten, Marcus Jäger, Juergen Becker, Joachim Windolf, Mohssen Hakimi
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Platelet-rich plasma or hyaluronate in the management of osteochondral lesions of the talus
Mei-Dan O, Carmont MR, Laver L, Mann G, Maffulli N, Nyska M.
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Platelet-rich Plasma Promotes Healing of Osteoporotic Fractures
Linwei Chen, MD; Xiaobo Yang, MD; Gao Huang, MS; Dianwen Song, MD; Xue-Shi Ye, MD; Huazi Xu, BS; Wanli Li, MD
Orthopedics
2013 -
Platelet-rich plasma releasate inhibits inflammatory processes in osteoarthritic chondrocytes
van Buul GM, Koevoet WL, Kops N, Bos PK, Verhaar JA, Weinans H, Bernsen MR, van Osch GJ.
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Platelet-rich plasma stimulates cell proliferation and enhances matrix gene expression and synthesis in tenocytes from human rotator cuff tendons with degenerative tears
Chris Hyunchul MD; Ji Eun Kim MS; Kang Sup Yoon, MD; Sue Shin, MD
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Platelet-Rich Plasma Therapy: A Systematic Literature Review and Evidence For Clinical Use
Lauren H. Redler, MD; Scott A. Thompson, MD; Stephanie H. Hsu, MD; Christopher S. Ahmad, MD and William N. Levine, MD
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Platelet-Rich Plasma Treatment Improves Outcomes for Chronic Proximal Hamstring Injuries in an Athletic Population
Ryan R. Fader, Justin J. Mitchell, Shaun Traub, Roger Nichols, Michelle Roper, Omer Mei Dan, Eric C. McCarty
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Platelet-Rich Plasma Use in Anterior Cruciate Ligament Surgery: Systematic Review of the Literature
David Figueroa, M.D., Francisco Figueroa, M.D., Rafael Calvo, M.D., Alex Vaisman, M.D., Ximena Ahumada, M.D., Sergio Arellano, M.D.
Arthroscopy: The Journal of Arthroscopic and Related Surgery
2015
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Platelet-rich plasma versus autologous whole blood for the treatment of chronic lateral elbow epicondylitis: a randomized controlled clinical trial
Thanasas C, Papadimitriou G, Charalambidis C, Paraskevopoulos I, Papanikolaou A.
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Platelet-Rich Plasma: A Literature Review
Navneet Arora DDS, Thaminda Ramanayake MS, Yan-Fang Ren DDS, MD, PhD, Georgios Romanos DDS, DrMedDent, PhD
Implant Dentistry
2009 -
Platelet-Rich Plasma: A Milieu of Bioactive Factors
Boswell SG, Cole BJ, Sundman EA, Karas V, Fortier LA
Arthroscopy: The Journal of Arthroscopic and Related Surgery
2012
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Platelet-Rich Plasma: Any Substance Into It?
O. M-Dan, G. Mann, N. Maffulli
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Platelet-rich Plasma: Current Concepts and Application in Sports Medicine
Michael P. Hall, MD, Phillip A. Band, PhD, Robert J. Meislin, MD, Laith M. Jazrawi, MD and Dennis A. Cardone, DO
Journal of the American Academy of Orthopaedic Surgeons
2009 -
Platelet-rich plasma: evidence for the treatment of patellar and Achilles tendinopathy - a systematic review.
Di Matteo B, Filardo G, Kon E, Marcacci M
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Platelet-Rich Plasma: From Basic Science to Clinical Applications
Foster TE, Puskas BL, Mandelbaum BR, Gerhardt MB, Rodeo SA.
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Platelet-rich plasma: growth factor enhancement for bone grafts
Robert E Marx, DDS, Eric R Carlson, DMD, Ralph M Eichstaedt, DDSc, Steven R Schimmele, DDS, James E Strauss, DMD, Karen R Georgefff (RN)
Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics
1997
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Platelet-rich Plasma: Intra-Articular Knee Injections Produced Favorable Results on Degenerative Cartilage Lesions
Elizaveta Kon, Roberto Buda, Giuseppe Filardo, Alessandro Di Martino, Antonio Timoncini, Annarita Cenacchi, Pier Maria Fornasari, Sandro Giannini and Maurilio Marcacci
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Platelet-Rich Plasma: New Clinical Application a Pilot Study for Treatment of jumper's knee
Elizaveta Kon, Giuseppe Filardo, Marco Delcogliano, Mirco Lo Presti, Alessandro Russo, Alice Bondi, Alessandro Di Martino, Annarita Cenacchi, Pier Maria Fornasari , Maurilio Marcacci
Injury Journal
2009 -
Platelet-Rich Plasma: Quantification of Growth Factor Levels and the Effect on Growth and Differentiation of Rat Bone Marrow Cells
Juliette Van Den Dolder, Rob Mooren, Annelies P.G. Vloon, Paul J.W. Stoelinga, and John A. Jansen
Tissue Engineering
2006
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Platelet-Rich Plasma: The PAW Classification System
Jeffrey M. DeLong, B.Sc.; Ryan P. Russell, M.A.; Augustus D. Mazzocca, M.S., M.D
Arthroscopy: The Journal of Arthroscopic and Related Surgery
2012 -
Platelet-rich plasma: why intra-articular? A systematic review of preclinical studies and clinical evidence on PRP for joint degeneration
G. Filardo, E. Kon, A. Roffi, B. Di Matteo, M. L. Merli, M. Marcacci
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Platelet-Rich Therapies in the Treatment of Orthopaedic Sport Injuries
Mikel Sanchez, Eduardo Anitua, Gorka Orive, Iñigo Mujika, Isabel Andia
Sports Medicine
2009
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Poor standardization in platelet-rich therapies hampers advancement
Sánchez M, Anitua E, Andia I.
Arthroscopy: The Journal of Arthroscopic and Related Surgery
2010 -
Positive Effect of an Autologous Platelet Concentrate in Lateral Epicondylitis in a Double-Blind Randomized Controlled Trial: Platelet-Rich Plasma Versus Corticosteroid Injection With a 1-Year Follow-up
Joost C. Peerbooms, MD; Jordi Sluimer, MD; Daniël J. Bruijn, PhD; Taco Gosens, PhD
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Potential of endogenous regenerative technology for in situ regenerative medicine
Eduardo Anitua, Mikel Sánchez, Gorka Orive
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Powered bone marrow biopsy procedures produce larger core specimens, with less pain, in less time than with standard manual devices
Larry J. Miller; Thomas E. Philbeck; Diana F. Montez; Tatiana A. Puga; Kim E. Brodie; Stephen C. Cohen; Cathy Spadaccini; Ronan Swords; Andrew J. Brenner
Hematology Reports
2011 -
Reciprocal Actions of Platelet-Secreted TGF-B1 on the Production of VEGF and HGF by Human Tendon Cells
Eduardo Anitua MD, Mikel Sanchez MD, Alan T. Nurden PhD, Mar Zalduendo PhD, Maria de la Fuente PhD, Juan Azofra MD, Isabel Andia PhD
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Reduced levels of mesenchymal stem cells at the tendon–bone interface tuberosity in patients with symptomatic rotator cuff tear
Philippe Hernigou; Guillaume Merouse; Pascal Duffiet; Nathalie Chevalier; Helene Rouard
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Release kinetics of platelet-derived and plasma-derived growth factors from autologous plasma rich in growth factors
Anitua E, Zalduendo MM, Alkhraisat MH, Orive G.
Annals of Anatomy
2013 -
Repeated platelet concentrate injections enhance reparative response of microfractures in the treatment of chondral defects of the knee: An experimental study in an animal model
Giuseppe Milano, M.D., Laura Deriu, M.D., Eraldo Sanna Passino, D.V.M., Gerolamo Masala, D.V.M. , Andrea Manunta, M.D. , Roberto Postacchini, M.D. , Maristella F. Saccomanno, M.D. , Carlo Fabbriciani, M.D.
Arthroscopy: The Journal of Arthroscopic and Related Surgery
2012 -
Rotator cuff repair healing influenced by platelet-rich plasma construct augmentation
Barber FA, Hrnack SA, Snyder SJ, Hapa O.
Arthroscopy: The Journal of Arthroscopic and Related Surgery
2011
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Shedding light in the controversial terminology for platelet rich products
Anitua E, Sánchez M, Orive G, Andía I.
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Single injection of platelet-rich plasma (PRP) for the treatment of refractory distal biceps tendonitis: long-term results of a prospective multicenter cohort study
Ilknur Sanli, MD; Barnes Morgan, MD; Fiek van Tilborg, MD; Lennard Funk, MD and Taco Gosens, MD
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Spinal Fusion Using an Autologous Growth Factor Gel and a Porous Resorbable Ceramic
William R. Walsh, Andreas Loefler, Sean Nicklin, Doug Arm, Ralph E. Stanford, Yan Yu, Richard Harris, R.M. Gillies
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Successful use of platelet-rich plasma for chronic plantar fasciitis.
O'Malley MJ, Vosseller JT, Gu Y.
HSS Journal
2013
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Tendon healing and platelet-rich plasma therapies
Isabel Andia, PhD, Mikel Sanchez and Nicola Maffulli
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The Anti-inflammatory and Matrix Restorative Mechanisms of Platelet-Rich Plasma in Osteoarthritis
Emily A. Sundman, DVM; Brian J. Cole, MD, MBA: Vasili Karas, MD; Craig Della Valle, MD; Matthew W. Tetreault, MD; Hussni O. Mohammed, DVM, PhD; Lisa A. Fortier, DVM, PhD
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The Basic Science of Platelet-rich Plasma (PRP): What Clinicians Need to Know
Arnoczky SP, Shebani-Rad S.
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The Biology of Platelet-Rich Plasma and Its Application in Oral Surgery: Literature Review
Dimitris Nikolidakis DDS, MSc and John Jansen, DDS PhD
Tissue Engineering
2008 -
The Biomechanical and Histologic Effects of Platelet-Rich Plasma on Rat Rotator Cuff Repairs
Jennifer Beck, MD; Douglas Evans, MD; Pietro M. Tonino, MD; Sherri Yong, MD; and John J. Callaci, PhD
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The effect of autologous conditioned plasma on the treatment of focal chondral defects of the knee. An experimental study
Milano G, Deriu L, Sanna Passino E, Masala G, Saccomanno MF, Postacchini R, Fabbriciani C.
International Journal of Immunopathology and Pharmacology
2011
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The effect of platelet-derived growth factors on knee stability after anterior cruciate ligament reconstruction: a prospective randomized clinical study
Vogrin M, Rupreht M, Crnjac A, Dinevski D, Krajnc Z, Recnik G
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The Effect of Platelet-Rich Fibrin Matrix on Rotator Cuff Tendon Healing: A Prospective, Randomized Clinical Study
Scott A. Rodeo, Demetris Delos, Riley J. Williams, ROnald S. Adler, Andrew Pearle and Russell F. Warren
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The Effect of Platelet-Rich Plasma and Bone Marrow on Murine Posterolateral Lumbar Spine Arthrodesis with Bone Morphogenetic Protein
Raj D. Rao, MD; Krishnaj Gourab, MD; Vaibhav B. Bagaria, MD; Vinod B. Shidham, MD; Umesh Metkar, MD; Brian C. Cooley, PhD
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The Effect of Platelet-Rich Plasma on Clinical Outcomes in Lateral Epicondylitis
Zafar Ahns, M.Phil., M.R.C.S., M.B.B.S., B.Sc., Roger Brooks, Ph.D., Sertaz-Niel Kang, F.R.C.S, Holly Weaver, B.A, Ian Nunney, M.Sc., B.Sc., Graham Tytherleigh-Strong, M.D., F.R.C.S. , Neil Rushton, M.D., F.R.C.S
Arthroscopy: The Journal of Arthroscopic and Related Surgery
2013 -
The Effect of Platelet-Rich Plasma on Posterolateral Lumbar Fusion in a Rat Model
Kamoda H, Ohtori S, Ishikawa T, Miyagi M, Arai G, Suzuki M, Sakuma Y, Oikawa Y, Kubota G, Orita S, Eguchi Y, Yamashita M, Yamauchi K, Inoue G, Hatano M, Takahashi K.
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The effects of plasma rich in growth factors (PRGF-Endoret) on healing of medial collateral ligament of the knee
Tomokazu Yoshioka, Akihiro Kanamori, Toshikatsu Washio,Katsuya Aoto, Kenta Uemura, Masataka Sakane, Naoyuki Ochiai
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The effects of PRGF on bone regeneration and on titanium implant osseointegration in goats: A histologic and histomorphometric study
Anitua E, Orive G, Pla R, Roman P, Serrano V, Andía I.
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The Future: Optimizing the Healing Environment in Anterior Cruciate Ligament Reconstruction
Mikel Sánchez MD, Eduardo Anitua MD, Emilio Lopez-Vidriero MD, Isabel Andía PhD
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The Impact of Plasma Rich in Growth Factors on Clinical and Biological Factors Involved in Healing Processes after Third Molar Extraction
Marco Mozzati, Germana Martinasso, Renato Pol, Carolina Polastri, Antonio Cristiano, Giuliana Muzio, Rosa Canuto
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The importance of understanding what is platelet-rich growth factor (PRGF) and what is not
Anitua E, Sánchez M, Orive G.
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The in vitro effect of different PRP concentrations on osteoblasts and fibroblasts
Filippo Graziani, Saso Ivanovski, Silvia Cei, Francesco Ducci, Maurizio Tonetti, Mario Gabriele
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The In Vitro Effects of Bupivacaine on Articular Chondrocytes
Constance Chu MD, Nicholas J. Izzo PhD, Nicole Papas BS, CH Coyle, A. Logar
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The inflammatory response: friend or enemy for muscle injury?
H Toumi and T Best
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The neutrophilic leukocyte in wound repair: A study with antineutrophil serum
David M. Simpson and Russell Ross
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The OnControl bone marrow biopsy technique is superior to the standard manual technique for hematologists-in-training: a prospective, randomized comparison
Reed LJ; Raghupathy R.; Strakhan M.; Philbeck T.E.; Kim M.Y.; Battini R.; Hussain Z.; Abdullah S.; Schweber S.; Bala K.; Pacello T.
Hematology Reports
2011
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The polymorphonuclear leukocyte - does it have a role in fracture healing
Grøgaard B, Gerdin B, Reikerås O.
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The positive effects of different platelet-rich plasma methods on human muscle, bone, and tendon cells
Mazzocca AD, McCarthy MB, Chowaniec DM, Dugdale EM, Hansen D, Cote MP, Bradley JP, Romeo AA, Arciero RA, Beitzel K
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The potential impact of the preparation rich in growth factors (PRGF) in different medical fields
Anitua E, Sánchez M, Orive G, Andía I.
Biomaterials
2007
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The Regenerative Effects of Platelet-Rich Plasma on Meniscal Cells In Vitro and Its In Vivo Application with Biodegradable Gelatin Hydrogel
Kazunari Ishida MD, Ryosuke Kuroda MD, Masahiko Miwa MD, Yasuhiko Tabata, PhD D.MedSc. D Pharm and Akishige Hokugo DDS, PhD and Teruya Kawamoto MD, Ken Sasaki MD, Minoru Doita MD, Masahiro Kurosaka MD
Tissue Engineering
2007 -
The role of platelet-rich plasma in inducing musculoskeletal tissue healing
Halpern BC, Chaudhury S, Rodeo SA.
HSS Journal
2012 -
The Roles of Growth Factors in Tendon and Ligament Healing
Timothy Molloy, Yao Wang, George A.C. Murrell
Sports Medicine
2003
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The treatment of intractable plantar fasciitis with platelet-rich plasma injection
Kumar V, Millar T, Murphy PN, Clough T.
The Foot
2013 -
The Use of Autologous Concentrated Growth Factors to Promote Syndesmosis Fusion in the Agility Total Ankle Replacement. A Preliminary Study
J. Chris Coetzee, MD, Gregory Pomeroy MD, David Watts MD, Craig Barrow MD
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The use of plasma-rich growth factors (PRGF) in oral surgery
Eduardo Anitua, MD, DDS
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The Use of Platelet-Rich Plasma in Arthroscopy and Sports Medicine: Optimizing the Healing Environment
Emilio Lopez-Vidriero, M.D., Ph.D., Krista A. Goulding, M.D., David A. Simon, M.D., Mikel Sanchez, M.D., Donald H. Johnson, M.D., F.R.C.S.C.
Arthroscopy: The Journal of Arthroscopic and Related Surgery
2010 -
The Use of Platelet-rich Plasma in Orthopedic Injuries
Willits K, Kaniki N, Bryant D.
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The Use of PRP in Ligament and Meniscal Healing
Braun HJ, Wasterlain AS, Dragoo JL.
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Treatment of Achilles Tendinopathy with Platelet-Rich Plasma
Gaweda K, Tarczynska M, Krzyzanowski W
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Treatment of Chronic Elbow Tendinosis With Buffered Platelet-Rich Plasma
Allan Mishra, MD and Terri Pavelko, PAC, PT
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Treatment of Knee Joint Osteoarthritis with Autologous Platelet-Rich Plasma in Comparison with Hyaluronic Acid
Spaková, Tímea PhD; Rosocha, Ján DVM, PhD; Lacko, Marek MD; Harvanová, Denisa PhD; Gharaibeh, Ahmed MD
American Journal of Physical Medicine and Rehabilitation
2012
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Treatment of Muscle Injuries by Local Administration of Autologous Conditioned Serum: A Pilot Study on Sportsmen with Muscle Strains
P Klein, P. Wehling, LM Mir, HJ Appell and T. Wright-Carpenter
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Treatment of osteochondral injuries with platelet gel
Marcus Vinicius Danieli, MD; Hamilton da Rosa Pereira, MD; Carlos Augusto de Sá Carneiro, MD; Sérgio Luiz Felisbino, MD and Elenice DeffuneII, MD
Clinics (Sao Paulo)
2014 -
Treatment of Partial Ulnar Collateral Ligament Tears in the Elbow with Platelet-Rich Plasma
Luga Podesta, MD; Scott A. Crow, MD; Dustin Volkmer, MD; Timothy Bert, MD; and Lewis A. Yocum, MD
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Treatment of solitary bone cysts with allogenic bone graft and platelet-rich plasma A preliminary report
Pedzisz P, Zgoda M, Kocon H, Benke G, Górecki A
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Treatment of Tendon and Muscle Using Platelet-Rich Plasma
Allan Mishra, MD and James Woodall Jr, MD and Amy Vieira, PAC
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Ultrasound guided injections of platelets rich plasma for muscle injury in professional athletes. Comparative study.
Bubnov R, Yevseenko V, Semeniv I.
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Ultrasound-guided injection of platelet-rich plasma in chronic Achilles and patellar tendinopathy
Ferrero G, Fabbro E, Orlandi D, Martini C, Lacelli F, Serafini G, Silvestri E, Sconfienza LM.
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Ultrasound-guided platelet-rich plasma injections for the treatment of osteoarthritis of the hip
Sánchez M, Guadilla J, Fiz N, Andia I
Rheumatology
2012 -
Use of Autologous Growth Factors in Lumbar Spinal Fusion
Lowery GL, Kulkarni S, Pennisi AE.
The Bone Journal
1999
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Use of Autologous Platelet-rich Plasma to Treat Muscle Strain Injuries
Jason W. Hammond, MD, Richard Y. Hinton, MD, MPH, Leigh Ann Curl, MD, Joaquin M. Muriel, PhD and Richard M. Lovering, PhD, PT
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Use of platelet rich plasma for the treatment of bicipital tendinopathy in spinal cord injury: a pilot study
Ibrahim VM, Groah SL, Libin A, Ljungberg IH, Aufiero D, Patel K, Sampson S
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Use of platelet rich plasma to treat plantar fasciitis: design of a multi centre randomized controlled trial
Joost Peerbooms, Wilbert van Laar, Frank Faberm, Hans M. Schuller, Henk van der Hoeven, Taco Gosens
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Use of Platelet-Leukocyte Membrane in Arthroscopic Repair of Large Rotator Cuff Tears: A Prospective Randomized Study
Stefano Gumina, MD, PhD; Vincenzo Campagna, MD; Giancarlo Ferrazza, MD; Giuseppe Giannicola, MD; Francesco Fratalocchi, PHT; Alessandra Milani, MS; Franco Postacchini, MD
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Use of Platelet-Rich Plasma for the Treatment of Refractory Jumper's Knee
Giuseppe Filardo, Elizaveta Kon, Stefano Della Villa, Ferruccio Vincentelli, Pier Maria Fornasari, Maurilio Marcacci
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Use of platelet-rich plasma in the care of sports injuries: our experience with ultrasound-guided injection
Bernuzzi G, Petraglia F, Pedrini MF, De Filippo M, Pogliacomi F, Verdano MA, Costantino C.
Blood Transfusion
2013 -
Use of Platelet-Rich Plasma to Enhance Tendon Function and Cellularity
John G. Lane, MD, Robert M. Healey, BS, MBA, Derek C. Chase, MD, and David Amiel, PhD
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Using a powered bone marrow biopsy system results in shorter procedures, causes less residual pain to adult patients, and yields larger specimens
James R Berenson; Ori Yellin; Brent Blumenstein; Deanna Bojanower; Jonathan Croopnick; David Aboulafia; Gargi Upadhyaya; Cathy Spadaccini
Diagnostic Pathology
2011
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Using the Growth Factors-Enriched Platelet Glue in Spinal Fusion and its Efficiency
Chun-Hao Tsai MD, Horng-Chaung Hsu MD, Yen-Jen Chen MD, Mou-Jyn Lin MD, Hsien Te Chen MD
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Variability of Platelet-rich Plasma Preparations
Russell RP, Apostolakos J, Hirose T, Cote MP, Mazzocca AD.
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What do we mean by the term “inflammation”? A contemporary basic science update for sports medicine
A Scott, K Khan, C Roberts, J Cook, and V Duronio
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Wound Healing in the PU.1 Null Mouse - Tissue Repair is not Dependent on Inflammatory Cells
Paul Martin, Deana D'Souza, Julie Martin, Richard Grose, Lisa Cooper, Rich Maki, Scott McKercher
Current Biology
2003 -
Wound healing--an overview of acute, fibrotic and delayed healing
Diegelmann RF, Evans MC
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