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Jack Farr II, MD, (Indianapolis, IN) and Brian Cole, MD, MBA, (Chicago, IL) discuss various treatment options available for medium-sized articular cartilage lesions. Depending on lesion location, patient age and comorbidities, treatment options may range between BioCartilage® Cartilage Extracellular Matrix augmented marrow stimulation, Cartiform®* Viable Osteochondral Allograft and especially in revision procedures, Fresh Osteochondral Allograft. *Cartiform is a registered trademark of Osiris Therapeutics, Inc.